Scientific Vita
Publi­cations
Con­tact

Prof. Dr.

Hartmut Hengel

Academic Education and University Degrees

1998
Habilitation in Virology, University of Munich, Germany,
1989
MD, University of Ulm, Germany supervised by Prof. Dr. Hermann Wagner, Institute of Microbiology, Department of Immunology
1987
Medical license
1981 - 1987
Study of Medicine at Ulm University, Germany

Employment

Since 11/2012
Full professor and Director of the Institute of Virology, Albert-Ludwigs- University Freiburg, Germany
2004 - 2012
Full professor and Director of the Institute of Virology, Heinrich-Heine University Düsseldorf, Germany
2002
Director and Professor at Robert Koch-Institute, Berlin, Germany
2002
Chairperson of the study group „Immunobiology of Viral Infections“ of the "Gesellschaft für Virologie" (GfV)
2001
Acting director, Department Infectious Diseases, Robert Koch-Institute Berlin, Germany
2001
Teaching license in the field of Virology, Freie Universität Berlin, Germany
2000 - 2004
Director, Division of viral infections, Robert Koch-Institute Berlin, Germany
1996 - 1999
Group leader at the Gene Center, Ludwig-Maximilians-University Munich and at the Virology chair of Max von Pettenkofer Institute of LMU Munich, Germany (Prof. Dr. Ulrich H. Koszinowski)
1995-1996
Training in Hospital and Environment Hygiene, Department of Hygiene and Med. Microbiology, Hygiene Institute, Heidelberg University, Germany (Prof. Dr. H.-G. Sonntag)
1994 - 1995
Training in pediatrics, university pediatric clinic Heidelberg, Germany (Prof. Dr. Hans Joachim Bremer)
1993 - 1996
Scientist, Hygiene-Institute of Ruprecht-Karls-University Heidelberg, Department of Virology, Germany (Prof. Dr. Ulrich H. Koszinowski)
1993
Guest Scientist, University of Leiden, The Netherlands, Department of Immunohematology and Blood Bank (Dr. E. Goulmy)
1990 - 1993
University of Ulm, Germany, Institute of Microbiology, Department of Virology (Prof. Dr. Ulrich H. Koszinowski)
Rölle A, Pollmann J, Ewen EM, Halenius A, Hengel H, Cerwenka A. 2014. CD14+cells, IL-12 and HLA-E drive NKG2C+NK cell expansion in HCMV infection. J Clin Invest 124: 5305 - 16.
Corales-Aguilar E, Trilling M, Hunold K, Fiedler M, Le VTK, Reinhard H, Ehrhardt K, Mercé- Maldonado E, Alijev E, Zimmermann A, Johnson DC, Hengel H. 2014. Human Cytomegalovirus Fcγ Binding Proteins gp34 and gp68 Antagonize Fcγ Receptors I, II and III. PLoS Pathog 10: e1004131.
Corrales-Aguilar E, Hoffmann K, Hengel H. 2014. CMV-encoded Fcγ receptors: modulators at the interface of innate and adaptive immunity. Seminars in Immunopathology 36: 627 - 40
Corrales-Aguilar E, Trilling M, Reinhard H, Mercé-Maldonado E, Widera M, Schaal H, Zimmermann A, Mandelboim O, Hengel H. 2013. A novel assay for detecting virus-specific antibodies triggering activation of Fcγ receptors. J Immunol Methods 387: 21 - 35.
Stern-Ginossar N, Weisburd B, Michalski A, Le VTK, Hein MY, Huang SX, Ma M, Shen B, Qian SB, Hengel H, Mann M, Ingolia NT, Weissman J.S. 2012. Decoding human cytomegalovirus. Science 338: 1088 - 1093.
Le VTK, Trilling H, Hengel, H. 2011. The cytomegaloviral protein pUL138 acts as potentiator of TNF receptor 1 surface density to enhance ULb’-encoded modulation of TNF-α signaling. J Virol 85: 13260–3270.
Halenius A, Hauka S, Dölken L, Stindt J, Reinhardt H, Wiek C, Hanenberg H, Koszinowski UH, Momburg F, Hengel H. 2011. Human cytomegalovirus disrupts the MHC class I peptide loading complex (PLC) and inhibits tapasin gene transcription. J Virol 85:3473 - 3485.
Trilling M, Le VTK, Fiedler M, Bleifuß E, Zimmermann A, Hengel H. 2011. Cytomegaloviral interferon signalling antagonist pM27 recruits DDB1-Ubiquitin-Ligase-complexes to target STAT2 for proteasomal degradation. PLoS Pathog 7:e1002069.
Stern-Ginossar N, Elefant N, Zimmermann A, Wolf DG, Saleh N, Biton M, Horwitz E, Prokocimer Z, Prichard M, Goldman-Wohl D, Greenfield C, Yagel S, Hengel H, Altuvia Y, Margalit H, Mandelboim O. 2007. Host immune system gene targeting by a viral miRNA. Science 317:376- 381.
Lenac T, Budt M, Arapovic J, Hasan M, Zimmermann A, Simic H, Krmpotic A, Messerle M, Ruzsics Z, Koszinowski UH, Hengel H*, Jonjic S*. 2006. The herpesviral Fc receptor fcr-1 as a potent down-regulator of the NKG2D ligands MULT-1 and H60. J Exp Med 203:1843-2850. *co- corresponding authors
Address
Institute of Virology
University Medical Center Freiburg Hermann-Herder-Strasse 11
79104 Freiburg
eMail
hartmut.hengel@uniklinik-freiburg.de