TP01

Mechanisms of antiviral therapy-induced virus-specific CD8+ T cell restoration in chronic viral hepatitis

TP02

Viral escape from dominant virus-specific CD8+ T cell responses and restoration strategies in HBV mono- and HBV/HDV co-infection

TP03

Generation of effective antiviral CD4 T cell immunity in viral hepatitis and its association to unique signatures of transcription factors

TP04

Characterization of follicular T helper cell responses in viral hepatitis

TP05

Role of myeloid cells in the liver for antiviral immunity

TP06

Lymphotoxin β receptor signalling-dependent control of virus clearance in chronic hepatitis B virus and hepatitis C virus infections

TP07

Dissecting NK cell-mediated immune responses against hepatitis B virus and hepatitis C virus infection

TP08

Mechanisms of interferon induction by hepatitis D virus and impact of chronic innate immune activation on antiviral immunity

TP09

Determinants of success and failure to control hepatitis C virus infection by the interferon system

TP10

Strategies to harness an effective antiviral response targeting hepatitis B virus

TP11

Global effects on host cell signalling by continuous stimulation of innate antiviral responses in persistent viral infections

TP12

Role of the host stress response in the establishment of viral persistence: comparative analysis of HCV and HAV infection

TP13

Dynamics of antiviral T cell immunity against viral infection of the liver

TP14

Means of modification and degradation of hepatitis B virus cccDNA

TP15

Hepatitis B virus X-protein-mediated transcriptional regulation and stability of cccDNA

TP16

Unravelling the role of DNA repair in the formation of the hepatitis B virus cccDNA persistence reservoir

TP17

Contribution of innate immune responses to persistence versus clearance of hepatitis C and hepatitis A virus infections

TP18

Combinatorial knock-down/knock-out strategies to reconstitute anti-HBV immune responses and to eliminate persisting HBV cccDNA

TP19

Integrated Research Training Group “Immunovirology”

TP01A

Metabolic regulation of T cell exhaustion in chronic HBV infection.

Z1

Central tasks of the transregional collaborative research centre 179

Z2

Immune monitoring and Bioinformatics