TP01

Fate and function of memory-like virus-specific CD8+ T cells in chronic viral hepatitis

TP02

Virus-specific CD8+ T cell responses in hepatitis B virus/ hepatitis D virus co-infection: mechanisms of failure and strategies for restoration

TP04

Regulation of virus-specific CD4 T helper cell responses in viral hepatitis

TP05

The impact of hepatic myeloid cells on antiviral CD8 T cell immunity in the liver

TP06

Role of platelets in control and clearance of hepatitis B virus infection via modulation of liver tissue environment and metabolism

TP07

Dissecting NK cell reactivity against hepatitis B/D virus and in hepatitis C virus infection

TP09

Control of hepatitis C virus infection by the interferon system and virus – host co-evolution

TP10

Identification of systems properties determining the dynamics of the hepatitis B virus infection cycle and cross-talk to host cell responses

TP11

Effects of persistent antiviral signalling on tissue homeostasis and antiviral immunity

TP13

Dynamics of antiviral immunity against hepatitis B virus in the liver

TP14

Means of modification and degradation of hepatitis B virus cccDNA

TP15

Viral determinants and innate immunity in persistent hepatitis B virus and hepatitis D virus infections

TP16

Role of DNA repair, SUMOylation and nuclear bodies in the formation of the hepatitis B virus cccDNA persistence reservoir

TP17

Contribution of innate immune responses to persistence versus clearance of hepatitis C virus and hepatitis A virus infections

TP18

Combinatorial knock-down/knock-out strategies to reconstitute antiviral im-munity and eliminate persisting hepatitis B virus cccDNA

TP19

Integrated Research Training Group “Immunovirology”

TP20

Impact of interferon-stimulated genes on virus-specific CD8+ T cells and NK cells in viral hepatitis

TP21

Metabolic regulation of the virus-specific T cell response in viral hepatitis

TP22

Impact of the enteric stage of hepatitis A virus and hepatitis E virus on the outcome of liver infection

TP23

Dynamics of hepatitis B virus morphogenesis and its alterations during chronic infection

Z01

Central tasks of the transregional collaborative research centre 179

Z02

High-resolution multi-parametric cell and tissue analysis

Z03

Experimental and computational single-cell sequencing