TRR179 - Thursday Lunch Lectures

12 | 02 | 2021

Events


Dirk Wohlleber (TP13) will talk about "Plasticity of T cells in the liver during viral infection" during the lunch lecture.

Canadian Liver Meeting 2022

11 | 25 | 2021

Events




The meeting will take place as hybrid meeting on May 13-15th, 2022. Featured amongst others by our cooperation partners CanHepC!
Read more...

IRTG Cafe

11 | 23 | 2021

Events


Today Marco Binder is open for to talk about his career and to answer questions...

TRR179 Seminar Series Freiburg

11 | 22 | 2021

Events


Dr. Enrico Lugli (Rozzano, Italy) will give a talk about "T cell immune responses in human cancer"

Highly cited researchers 2021

News


Recognizing the most influential researchers 2021
Our speaker, Ralf Bartenschlager is also in 2021 among the top one percent of the most cited experts in his field. Even more: Mathias Heikenwälder, one of our PIs also counts to the most highly cited researchers world wide! Congratulations!!Further details can be found here: https://bit.ly/3qEBjxg

( 11 | 18 | 2021 )

TRR179 Seminar Series Munich

11 | 15 | 2021

Events




We would like to cordially invite you to our next seminar held by Prof. Dr. Ulrike Seifert of the Friedrich Loeffler-Institute, University of Greifswald on the following topic: ”Ubiquitination as regulator of the host cell response to bacto-viral infection”

IRTG Cafe

11 | 05 | 2021

Events


Prof. Dr. Ulrike Protzer, who is institute director of the Institute of Virology at Helmholtz Zentrum München and director of the Institute of Virology of TU München and PI of the TRR179 TP14 and TP18, will visit us and talk to us in a relaxed atmosphere

TRR179 THURSDAY LUNCH LECTURE

11 | 04 | 2021

Events


Dr. Maike Hofmann (TP20, Freiburg) will talk about "COVID-19 and CD8+ T cells"

Newsletter 5

News


We are proud to present you the next issue of our newsletter today under the download link
Read more...

( 10 | 28 | 2021 )

TRR179 goes Podcast

News


In the meantime we have two more episodes of our Podcast available.
Read more...

( 10 | 28 | 2021 )

CanHepC and TRR179 exchange program - call for application open

News


CanHepC and the German TRR179 Network are offering the opportunity for one CanHepC trainee and one student from the German TRR179 Hepatitis Network to do a 2-6 months internship with one the of PIs affiliated to the other network.
Read more...

( 10 | 19 | 2021 )

Post-doc position (f/m/d) in the field of antiviral immunology

Jobs


In a DFG-funded project on infection of the liver with hepatitis B viruses, we are characterizing the immune determinants for control of infection vs failure to control of infection. The focus of the project is on virus-specific CD8 T cells and the local hepatic regulation of their effector functions through environmental and cytokine-induced signals. The AG Wohlleber is looking for a Post-doctoral researcher to investigate the regulation and dynamics of CD8 T cell immunity and identify mechanisms or pathways that will decide whether an HBV infection will develop into acute or chronic infection.
Read more...

OPEN POSITION for a postdoctoral fellow in the research group of Ralf Bartenschlager at Heidelberg University

Jobs


The Bartenschlager group is studying the interaction between plus-strand RNA viruses such as Dengue and Zika virus, SARS-CoV-2 and Hepatitis C virus and their host cells. One major focus is the cell biology underlying virus – host cell interactions aiming to understand how viruses reprogram cells for robust viral replication with the goal to identify possible drug targets for antiviral therapy.
Read more...

Award winners

News


The Distinguished Award in Hepatitis B Research was presented to Michael Nassal and Stephan Urban. Both gave well-received presentation on their groundbreaking work during the HBV meeting 2021.

( 10 | 15 | 2021 )

TRR179 Thursday Lunch Lecture

10 | 07 | 2021

Events


Prof. Dr. Sabrina Schreiner will be on stage this time.

TRR179 - Seminar Series Heidelberg

09 | 21 | 2021

Events


Konstantin Sparrer, Ulm University, on ‘SARS-CoV-2 vs. Innate Immunity’

Seminar Series FREIBURG

09 | 20 | 2021

Events


Determining the essential functions of distinct pro-survival BCL-2 family members by using gene-swap mice

SAVE THE DATE 30./31.05.2022: Intl. Conference of the TRR179

News


We are delighted to invite you to our International Conference "Viral hepatitis and beyond: from basic science to cure" in Freiburg from May, 30-31, 2022.
Read more...

( 07 | 20 | 2021 )

TRR179 Seminar series Freiburg

07 | 05 | 2021

Events


Dr. Paola FISICARO (Laboratory of Viral Immunopathology, Azienda-Ospedaliero-Universitaria di Parma) will talk about "From transcriptomic to functional characterization of virus-specific CD8 T cells in chronic hepatitis B to identify novel molecular targets for therapeutic T cell reconstitution strategies”.

Hepatitis researcher honored

News




Junior research group leader Dr. Maike Hofmann (TP21) has been honored...
Read more...

( 07 | 02 | 2021 )

TRR179 seminar series Munich

06 | 30 | 2021

Events


Seminar talk given by Prof. Dr. Maura Dandri (UKE Hamburg and DZIF) as guest in Munich on
June 30th 2021 at 03:30 pm about “HBV cccDNA silencing: a key step towards functional cure?“

IRTG-Cafe 02. July 2021

06 | 23 | 2021

Events


IRTG Cafe with Ulrike Protzer
Read more...

TRR179 seminar series

06 | 14 | 2021

Events


Professor Maini (UCL Division of Infection and Immunity, London) will talk about “Rescuing HBV-specific CD8 T cells from the tolerogenic liver niche“

TRR179 Seminar series

05 | 18 | 2021

Events


Dr. Paul Ahlquist (University of Wisconsin-Madison, USA) will talk about "Mechanistic insights from structure-function studies of positive-strand RNA virus replication complexes"

TRR179 goes Podcast

News


We are happy to share our first TRR179 podcast with you!


Enjoy listening!!!
Read more...

( 05 | 12 | 2021 )

CONGRATULATION

News


NEW graduate school funded by DFG
Read more...

( 05 | 11 | 2021 )

TRR179 - seminar series Heidelberg

04 | 20 | 2021

Events


Our next guest, Dr. Volker Thiel will talk about "SARS-CoV2: From Genome to Function" online on Tuesday, April 20 at 17:15.
We are looking forward to get the latest information of his research findings.

Thursday Lunch Talk

04 | 15 | 2021

Events


Prof. Dr. Prof. Dr. Adelheid Cerwenka (TP07) will talk about "TNK cells and anti-viral immunity"

Seminar Series Heidelberg

04 | 01 | 2021

Events


Dr. Florian Krammer (Mount Sinai Hospital, New York, USA)
‘Antibody responses to SARS-CoV-2 infection and vaccination’

Virtual Meeting

TRR179 - Online Seminar

04 | 01 | 2021

Events


Our guest, Dr. John Schoggins from the University of Texas Southwestern Medical Center (Dallas, USA) will talk about "Host-based antiviral mechanisms targeting coronavirus and flavivirus"

Thursday Lunch lecture

03 | 18 | 2021

Events


Prof. Dr. Dirk Grimm (TP18) will talk about "The fast and the curious - high-throughput interrogation of viral vector libraries in vitro and in vivo"

IRTG Cafe - Online

03 | 12 | 2021

Events


TRR179 project leader (TP20) Maike Hofmann will talk about her career and the compatibility of work and family...especially in rough pandemic times!

TRR179: A collaborative research network on hepatitis virus persistence and antiviral immunity

03 | 03 | 2021

Events


Ralf Bartenschlager will introduce our TRR179 to our collaborative research partners of the SFB "Jak-Stat Monarchies" in Vienna.

New cooperation

News


We are happy to announce our new cooperation with the Austrian SFB "JAK-STAT Monarchies"
Read more...

( 02 | 25 | 2021 )

CANCELLED: TRR179 - Seminar

02 | 16 | 2021

Events


CANNCELLED:
Dr. John Schoggins
"Host-based antiviral mechanisms targeting coronavirus and flavivirus"
Read more...

Kolloquium 2020 Immunity and Infection

02 | 15 | 2021

Events


Prof. Dr. Lars Engstrand of the Department of Microbiology, Tumor and Cell Biology (Karolinska Institute, Sweden) will talk about
"Studies of the human microbiome in health and disease"

IRTG Cafe

02 | 05 | 2021

Events


IRTG Cafe with Ursula Klingmüller
Read more...

Thursday Lunch Lecture

02 | 04 | 2021

Events


Prof Dr. Andreas Pichlmair, TP11 will talk about "Viruses and their nucleic acids: better get rid of them - but how?"

BEIJERINCK VIROLOGY PRIZE FOR RESEARCH ON HEPATITIS C

News


We are happy to announce that Ralf Bartenschlager, who is speaker of the TRR179, received the Beijerinck Virology Prize 2021

( 01 | 29 | 2021 )

IRTG Cafe 29.01.2021

01 | 29 | 2021

Events


The next IRTG Cafe will take place on Jan. 29th with Julija Miller, CRA at iOMEDICO
Read more...

Preise der deutschen Leberstiftung

News


Aktuelle Ausschreibungen
Read more...

( 01 | 15 | 2021 )

Thursday Lunch Talk

01 | 07 | 2021

Events


Prof. Dr. Percy A. Knolle (TP05) will talk about "Controlling T cell immunity in the liver – the famous and unknowns" this time - as before online of course.
Read more...

DFG - Für das Wissen entschieden

News


Mit “DFG2020 – Für das Wissen entscheiden” will die DFG ihre Überzeugung für eine freie und erkenntnisgeleitete Forschung in die Gesellschaft tragen. Den Anlass gab die Gründung der Vorgängerorganisation der DFG, der “Notgemeinschaft der Deutschen Wissenschaft”, im Jahr 1920. Unter dem Claim #fürdasWissen haben wir 2020 Gründe gesammelt, warum wir uns für das Wissen und die Wissenschaft entscheiden.

( 12 | 29 | 2020 )

TRR179 - IRTG Café - ONLINE

12 | 18 | 2020

Events




Insights into the career of P. Wimmer

Thursday Lunch Talk

12 | 17 | 2020

Events


PD Dr. Tobias Böttler (TP04) talks about "Clinical courses of acute and chronic viral hepatitis"

Hepatitis-D Mega-Deal for a drug "Made in Heidelberg"

News


A discovery by Heidelberg virologist Stephan Urban is worth billions.
Read more...

( 12 | 15 | 2020 )

Kick off Meeting

11 | 20 | 2020

Events


The Kick off meeting of the TRR179 for the second funding period took place ONLINE on 16./17.11.2020.
Read more...

Highly cited researchers

News


Recognizing the most influential researchers 2020
Read more...

( 11 | 19 | 2020 )

Thursday Lunch Talk

11 | 05 | 2020

Events


We start our new "Thursday Lunch talk series"
Read more...

TRR179 - IRTG Café - ONLINE

10 | 23 | 2020

Events


Career pathes and more...interactivity highly requested on Oct 23 from 12:00 - 14:00h!
Read more...

Seminar series in Heidelberg

10 | 20 | 2020

Events


RNA modifications at the virus-host interface
Read more...

Seminar Series - ONLINE - Oct. 19, 2020, 16:00h

10 | 19 | 2020

Events


Biochemical characterisation of endogenous human BAFF and APRIL
Read more...

Wegbereiter für Therapien

News


IRTG Kick off meeting

News




IRTG Kick off meeting for all students of the TRR179 took place as web conference on August 27th, 2020.
Read more...

( 08 | 26 | 2020 )

Neues Medikament zugelassen

News


In der nano Sendung des ZDF vom 20.08.2020 sehen Sie ab Minute 9:40min einen Beitrag von unserem TP-Projektleiter S. Urban zum Thema "Das Hepatitis D-Virus aussperren"
Read more...

( 08 | 21 | 2020 )

Leopoldina - Freiburg

News


Prof. Dr. Robert Thimme was appointed to the National Academy of Sciences, the Leopoldina. This election is considered one of the highest awards for researchers in Germany.
Read more...

( 08 | 13 | 2020 )

OPEN POSITION for a PhD student "Dynamics of hepatitis B virus morphogenesis and its alterations during persistent infection"

Jobs




An open position for a PhD student to analyse the dynamics of hepatitis B virus morphogenesis and its alterations during persistent infection is offered in the Department of Infectious Diseases, Molecular Virology in Heidelberg. We propose that HBV particles are subject to defined ultrastructural dynamics with a series of thermodynamically driven, temporally and spatially regulated events during particle morphogenesis. In this project, we aim at a detailed characterization of nucleocapsids containing the authentic replication complex by biochemical and structural biology methods in the frame of the TRR179.
More details
Read more...

Hepcludex approved

News


In Heidelberg, scientists spent decades researching an active substance against hepatitis D. Now the drug has been approved by the European Commission.This could give hope to millions of infected people. The leading researchers in this field is Prof. S. Urban, one of our project leaders in the TRR179.
Congratulations!

( 08 | 01 | 2020 )

EMBO announces newest elected members

News




EMBO has bestowed upon 63 leading scientists the lifetime honour of EMBO Membership in recognition of their remarkable achievements in the life sciences, it was announced today. “The new Members have contributed to the success of research in the life sciences in Europe and around the world,” said EMBO Director Maria Leptin. “As EMBO Members they can help to shape the future through EMBO’s work to support talented researchers, bring ideas together, and promote an international research environment conducive to excellent science.” One of the new elected EMBO members is Ursula Klingmüller (TP10)

( 07 | 07 | 2020 )

Second Funding Period TRR179

News


We are happy to announce that the TRR179 is beeing funded for another four year periode from July 1st , 2020 on. Stay tuned about the latest research results of our consortium here!!

( 07 | 01 | 2020 )

HIF-1α slows down NK cells

News


Adelheid Cerwenka demonstrated that extended inhibition of HIF-1α in mouse our human NK cells unleashes potent NK cell effector functions (Ni et al., Immunity 2020).
Read more...

( 05 | 26 | 2020 )

ERC Proof-of-concept grant for Mathias Heikenwälder

News


We are happy to announce that Mathias Heikenwälder received the prestigous ERC grant "Proof-of-concept".
Read more...

( 05 | 12 | 2020 )

Hepatitis B: New therapeutic approach

News


Ulrike Protzer, Percy Knolle, Mathias Heikenwälder and Dirk Grimm, all members of the TRR179, were able to show that in both models of HBV infection, mice that express hepatocyte-specific small hairpin RNAs or that were given subcutaneous injections of siRNAs had reduced levels of HBV antigens, HBV replication, and viremia compared to mice given control RNAs.
Read more...

( 02 | 10 | 2020 )

MEDIZIN AM ABEND - Hepatitis virus infections of the liver - the silent epidemic

02 | 10 | 2020

Events


Ralf Bartenschlager, who is speaker of the TRR179 and project leader of TP09 will give a public lecture on 12 February 2020 as part of the "Medizin am Abend" series (large lecture hall of the Kopfklinik, Im Neuenheimer Feld 400, starting at 7 pm).
Read more...

PRINCE MAHIDOL AWARD 2019 FOR RALF BARTENSCHLAGER

News


We are happy to announce that Ralf Bartenschlager, who is speaker of the TRR179, received the Prince Mahidol Award in the field of medicine.
Read more...

( 02 | 10 | 2020 )

TALK OF THOMAS PIETSCHMAN IN HEIDELBERG

02 | 10 | 2020

Events


Thomas Pietschmann will be in Heidelberg on Tuesday, February 18th talking on „Heterogeneity and plasticity: Keys for HCV vaccine research?“
Read more...

TALK OF ELEONORE BARNES IN MUNICH

01 | 07 | 2020

Events


Eleonore Barnes will be in Munich on 13.01.2020 talking on "The development of candidate vaccines for HBV immunotherapy-with lessons from HCV"
Read more...

Three "Highly cited researchers" in 2019

News


In 2019 we are happy to announce that three project leaders of the TRR179 appeared on the list of "Highly Cited Researchers". This international evaluation names researchers whose publications in their respective fields - a total of 21 disciplines in the natural, life and social sciences - have been cited most frequently worldwide or have produced outstanding publications across several disciplines.
Read more...

( 11 | 22 | 2019 )

TRR179 was part of the Night of Research in Heidelberg 2019

News


Together with the TRR209 "Liver Cancer", the SFB1129 and the SPP1923 we participated in the Night of Research in Heidelberg on Friday, 27.09.2019.
Read more...

( 10 | 25 | 2019 )

Ralf Bartenschlager was awarded with the Heinrich-Pette-Lecture

News


On September 12, 2019, Prof. Ralf Bartenschlager, winner of this year's Heinrich Pette Lecture, held his honorary lecture at the HPI entitled "Hepatitis C virus and its relatives: Quite similar, but so different".
Read more...

( 09 | 27 | 2019 )

Science Night in Heidelberg on Friday, September 27th 2019

09 | 27 | 2019

Events


The TRR179 will participate also this year participate in the Science Night in Heidelberg.
Read more...

TOX is important for T cell function

News


Robert Thimme, Percy Knolle and Dirk Wohlleber were part of a research team unravelling the role of TOX for T cells.
Read more...

( 08 | 20 | 2019 )

STEEVE BOULANT received the Loeffler-Frosch-Price of the German Society of Virology (GfV)

News


We congratulate Steeve Boulant on receiving the Loeffler-Frosch-Price of the German Society of Virology (GfV).
Read more...

( 05 | 08 | 2019 )

ANNE SCHÜTZ, STEEVE BOULANT, and STEFAN SEITZ are novel associated TRR179 members.

News


We are happy to welcome Anne Schütz, TU München, Steeve Boulant, University Hospital Heidelberg, and Stefan Seitz, University Hospital Heidelberg as novel group leaders associated to the TRR179!
Read more...

( 05 | 07 | 2019 )

TALK OF GEORG LAUER IN FREIBURG

03 | 21 | 2019

Events


Georg Lauer will be in Freiburg on 25/03/2019 talking on "Is cure of chronic infection also a cure for exhausted T cells?"
Read more...

Survival Strategies - Presentation TRR179

03 | 14 | 2019

Events


Within the seminar series "Survival Strategies" the TRR179 was presented.
Read more...

TALK OF MEIKE DITTMANN IN HEIDELBERG

03 | 12 | 2019

Events


Meike Dittmann will be in Heidelberg on 19/03/2019 talking on "Interferon-stimulated genes: The work horses of the interferon response".
Read more...

MAIKE HOFMANN received scholarship of the "Margarete von Wrangell habilitation programme for women".

News


We would like to congratulate Maike Hofmann on receiving the prestigious scholarship "Margarete von Wrangell-Habilitationsprogramm für Frauen".
Read more...

( 03 | 04 | 2019 )

VOLKER LOHMANN received the DZIF award for Translational Infection Research

News


We would like to congratulate Volker Lohmann, who was awarded a Prize for Translational Infection Research in honor of his scientific accomplishment.
Read more...

( 01 | 07 | 2019 )

Also in 2018 Two "Highly Cited Researchers" within TRR179

News


With Veit Hornung, LMU Munich and Ralf Bartenschlager, Heidelberg University two scientists of the TRR179 appeared again on the list of Highly Cited Researchers 2018. This international evaluation names researchers whose publications have been cited most frequently worldwide in their respective fields - a total of 21 disciplines in the natural, life and social sciences.
Read more...

( 11 | 30 | 2018 )

TRR179 was part of the Night of Research in Heidelberg

News


Together with the TRR209 "Liver Cancer", the TRR179 participated in the Night of Research in Heidelberg on Friday, 28.09.2018.
Read more...

( 10 | 01 | 2018 )

Cellular responses induced by a member of the Flaviviridae family

News


Zika Virus (ZIKV) is a close relative of the hepatitis C virus (HCV) and therefore, both viruses belong to the same family (Flaviviridae). However, while HCV causes a non-cytolytic chronic infection, ZIKV infections are lytic and do not persist.
Read more...

( 09 | 14 | 2018 )

Women in Science Conference in Münster in November 2018

09 | 14 | 2018

Events


The Women-in-Science Network Conference 2018 entitled ‘Decision Making in Infection and Immunity’, which is also supported by the TRR179, will be held in Munster from November 26 – 27, 2018.
Read more...

Talk of Jörg Timm in Freiburg 23/07/2018 4:15 pm

07 | 17 | 2018

Events


Jörg Timm will be in Freiburg on 23/07/2018 talking on "Viral and host adaptation in persistent infection – lessons from HBV and HCMV"
Read more...

50 years of Sonderforschungsbereiche (coordinated research centers)

News


In 2018, the program "Collaborative Research Centers" will be 50 years old.
Read more...

( 07 | 09 | 2018 )

Frontiers in Cancer Research (FCR) organized by Prof. Dr. Ursula Klingmüller and Dr. Susanne Weg-Remers

07 | 04 | 2018

Events


The conference FRONTIERS in CANCER RESEARCH 2018 which is organized by Prof. Dr. Ursula Klingmüller (Chair of the DKFZ Executive Women's Initiative; TRR179 project leader) and Dr. Susanne Weg-Remers (Vice-Chair of the DKFZ Executive Women's Initiative) provides an overview of the most exciting fields of current, interdisciplinary cancer research.
Read more...

Prize for the best poster at the TOLL 2018 Meeting in Porto, Portugal

News


We would like to congratulate Jasper Hesebeck-Brinckmann for winning the prize for the best poster at the TOLL 2018 Meeting in Porto, Portugal.
Read more...

( 06 | 22 | 2018 )

Talk of Paul Klenerman in Munich 25/06/2018 5:00 pm

06 | 20 | 2018

Events


Paul Klenerman will be in Munich on 25/06/2018 talking on "The (gradual) rise of memory inflation"
Read more...

Talk of Eberhardt Hildt in Freiburg

06 | 18 | 2018

Events


Eberhard Hildt will be in Freiburg on 18/06/2018 talking on "Infection research about hepatitis B virus: from basic research to the development of novel therapeutic strategies"
Read more...

Talk of Gregor Ebert in Munich 14/06/2018 5:00 pm

06 | 07 | 2018

Events


Gregor Ebert will be in Munich on 14/06/2018 talking on "Dying to survive: Killing infected cells to eliminate overwhelming infections"
Read more...

International Hepatitis Symposium TRR179 in Heidelberg May 16th to May 18th 2018

News


The first international symposium of the TRR179 in Heidelberg from May 17th to May 18th 2018 was a great success.
Read more...

( 06 | 07 | 2018 )

International Hepatitis Symposium TRR179 in Heidelberg May 16th to May 18th 2018

05 | 16 | 2018

Events


Register now
Read more...

Two new members associated

News


We are happy to announce that we have two novel groups associated to the TRR179.
Read more...

( 04 | 02 | 2018 )

Survival strategies

News


Life science in Heidelberg Club K
Read more...

( 02 | 20 | 2018 )

Survival Strategies

02 | 20 | 2018

Events


Heidelberg life science under discussion
Read more...

Seminar in Munich by Adelheid Cerwenka

02 | 05 | 2018

Events


Adelheid Cerwenka will be in Munich on 26/02/2018 talking on "Harnessing NK cells In viral infection and cancer"
Read more...

DFG Announces Veit Hornung as winner of 2018 Leibniz Prize

News


We are very pleased to announce that Veit Hornung, who is project leader in TRR179, has been awarded with the 2018 Leibniz Prize.
Read more...

( 01 | 08 | 2018 )

Talk of Andreas Puschnik in Munich on 08/01/2018

01 | 08 | 2018

Events


Andreas Puschnik will be in Munich on 08/01/2018 talking on "Identification of host factors for virus infections through CRISPR screens"
Read more...