TRR179 Seminar

08 | 09 | 2022

Events


Prof. Dr. Volker Lohmann (University of Heidelberg, Department of Infectious Diseases, Molecular Virology, CIID and TP17) will talk about "Assessing the RNA replication fitness of HCV isolates in cell culture: The return of the ISDR” in the lecture hall in Freiburg (Int. medicine)

World Hepatitis Day

News


World Hepatitis Day (WHD) takes places every year on 28 July bringing the world together under a single theme to raise awareness of the global burden of viral hepatitis and to influence real change. In 2022 the theme is ‘I Can’t Wait’. It’s also a day to celebrate the progress we have made and to meet the current challenges and an opportunity for us to jointly facilitate prevention, diagnosis and treatment.

( 07 | 28 | 2022 )

TRR179 Thursday Lunch Lecture

06 | 30 | 2022

Events


U. Protzer will talk about "Strategies to cure HBV"!

TRR179 Conference Report

News




We thank all speakers and participants of the conference for their contributions, which made the conference a memorable and worthwhile visiting event for all. To get some impressions and a wrap up, you are warmly invited to listen to our Podcast.

Enjoy listening!!!

( 06 | 23 | 2022 )

TRR179 Seminar Series - Heidelberg

06 | 21 | 2022

Events


Dr. Justin Bailey (Johns Hopkins University, School of Medicine, Baltimore, USA) will talk about "Convergent evolution of human bNAb lineages associated with control of HCV infection"

Wolfgang - Gerok Preis 2022

News


Stephan Urban (PI TP15) has been awarded with the first Wolfgang Gerok Price of the FALK Foundation 2022
Read more...

( 06 | 20 | 2022 )

Thursday Lunch Lecture

05 | 26 | 2022

Events


PD Dr. Carolin Mogler (Institute of Pathology, TUM School of Medicine, Technical University of Munich ), TP Z02
will speak on Infectious Hepatitis of men and mice!

TRR179 Seminar series Heidelberg

05 | 17 | 2022

Events


Dr. Michael Diamond (Washington University Medical School, St. Louis, USA) will talk about ‘Innate and adaptive immune protection against emerging SARS-CoV-2 variants’

Ernst Jung-Preis for Medicine 2022

News


Another prestigious award for the speaker of our consortium, Ralf Bartenschlager (Heidelberg).
Read more...

( 05 | 16 | 2022 )

CANADIAN LIVER MEETING 2022

05 | 13 | 2022

Events


CONGRÈS CANADIEN D'HÉPATOLOGIE,
May 13 – 15, 2022 (In-Person & Online)
Read more...

TRR179 NEWSLETTER 7

News


Just check the latest issue of our newsletter to get a wrapped up information about our consortium.

( 05 | 04 | 2022 )

Else-Kröner Scholarship of Excellence

News


Tobias Böttler (TP04) has been awarded with the Else Kröner Scholarship of Excellence from the Else Kröner Foundation for the project "Influence of antigen exposure and immunosuppression on pathogen-specific follicular T helper cells"
Read more...

( 05 | 01 | 2022 )

Thursday Lunch Lecture

04 | 07 | 2022

Events


My scientific pandemic side-step: Comparing cell manipulation by HCV and SARS-CoV-2
Read more...

Youth research award winner anno 1980

News


Undoubtedly a success story of our project leader Stephan Urban (TP15), which is highlighted in the artikel here https://www.stern.de/panorama/wissen/jugend-forscht--die-spannendsten-preistraeger-erzaehlen-ihre-geschichte-31721492.html

( 04 | 05 | 2022 )

Therapeutic vaccines for HBV

News




Read the views of Ulrike Protzer (TP14, TP18), Stephan Urban (TP15) and other leading experts in Nature's feature story on HBV cure. They discuss how to develop a curative therapy for people living with chronic hepatitis B by combining antivirals or stimulating the immune system using e.g. a therapeutic vaccine: pubmed.ncbi.nlm.nih.gov/35327662/

( 04 | 04 | 2022 )

German Cancer Award 2022 to Mathias Heikenwälder (TP06)

News


Another success story from our TRR that we are all very happy about. Prof. Dr. Mathias Heikenwälder, receives the German Cancer Award 2022 in the category "Experimental Cancer Research" for his outstanding basic research on chronic inflammation and liver cancer.
Read more...

( 03 | 30 | 2022 )

Dr. Maike Hofmann receives the Heinz Maier-Leibnitz Prize of the DFG

News


This was decided by a selection committee set up by the DFG and the Federal Ministry of Education and Research. The prize is considered the most important award for young scientists in Germany.
Read more...

( 03 | 09 | 2022 )

Thursday Lunch lecture

03 | 03 | 2022

Events


Volker Lohmann (TP17) will talk about "Innate immune response to HAV and HCV infection"

IRTG Cafe

02 | 25 | 2022

Events


Today Joachim Lupberger, a Group Leaderat Inserm U1110 (Strasbourg, France9 will give us an insight into his daily work.

TRR179 Seminar Series Freiburg

02 | 25 | 2022

Events


Prof. Susanne Herold (Gießen) will talk about "Macrophage (re-)programming in viral pneumonia: role in lung injury and stem-cell-mediated repair"

TRR179 Seminar Heidelberg

02 | 15 | 2022

Events


Barbara Rehermann (NIH) will talk about "Immunology of Chronic Hepatitis B and D: Beyond Virus-Specific T Cells"

TRR179 Lunch Lecture

02 | 03 | 2022

Events


The TRR179 Thursday Lunch Lecture in February 2022 will be held on Thursday, February 3, 2022 at 12.00 pm as Zoom meeting.

Prof. Dr. Dr. Andreas Pichlmair (TP11, TUM Munich) will talk about "Viral nucleic acids: their interactions with cellular proteins and degradation mechanisms"

Honorary doctoral degree of Mainz University Medicine for Professor Dr. Ralf Bartenschlager

News


Appreciation of his services to the transfer of knowledge from basic research to medical application for the treatment of hepatitis C
Read more...

( 02 | 03 | 2022 )

TRR179 Newsletter 6

News


Just check the latest issue of our newsletter to get a wrapped up information about our consortium.
Read more...

( 02 | 02 | 2022 )

TRR179 SEMINAR SERIES Heidelberg

01 | 18 | 2022

Events


Dr. Wolfgang Schamel from Freiburg University will talk about ‘Blocking the virus-induced translation shutdown in CoV-infected cells’ on Tuesday, January 18 2022 at 17:15 in our virtual meeting

IRTG Lunch Lecture

01 | 13 | 2022

Events


Today Macro Binder will talk about "The winner takes it all, and COVID19 likes to win – the dynamics of viral replication vs. cell-intrinsic immunity"

DZIF Award 2021

News


This year, the German Center for Infection Research (DZIF) honors the physician and clinical virologist Prof. Ulrike Protzer and co-speaker of our consortium (TP14, TP18, TUM Munich) for her scientific achievements with the DZIF Award for Translational Infection Research. Congratulations!

( 12 | 14 | 2021 )

TRR179 - Thursday Lunch Lectures

12 | 02 | 2021

Events


Dirk Wohlleber (TP13) will talk about "Plasticity of T cells in the liver during viral infection" during the lunch lecture.

Canadian Liver Meeting 2022

11 | 25 | 2021

Events




The meeting will take place as hybrid meeting on May 13-15th, 2022. Featured amongst others by our cooperation partners CanHepC!
Read more...

IRTG Cafe

11 | 23 | 2021

Events


Today Marco Binder is open to talk about his career and to answer questions...

TRR179 Seminar Series Freiburg

11 | 22 | 2021

Events


Dr. Enrico Lugli (Rozzano, Italy) will give a talk about "T cell immune responses in human cancer"

Highly cited researchers 2021

News


Recognizing the most influential researchers 2021
Our speaker, Ralf Bartenschlager is also in 2021 among the top one percent of the most cited experts in his field. Even more: Mathias Heikenwälder, one of our PIs also counts to the most highly cited researchers world wide! Congratulations!!Further details can be found here: https://bit.ly/3qEBjxg

( 11 | 18 | 2021 )

TRR179 Seminar Series Munich

11 | 15 | 2021

Events




We would like to cordially invite you to our next seminar held by Prof. Dr. Ulrike Seifert of the Friedrich Loeffler-Institute, University of Greifswald on the following topic: ”Ubiquitination as regulator of the host cell response to bacto-viral infection”

IRTG Cafe

11 | 05 | 2021

Events


Prof. Dr. Ulrike Protzer, who is institute director of the Institute of Virology at Helmholtz Zentrum München and director of the Institute of Virology of TU München and PI of the TRR179 TP14 and TP18, will visit us and talk to us in a relaxed atmosphere

TRR179 THURSDAY LUNCH LECTURE

11 | 04 | 2021

Events


Dr. Maike Hofmann (TP20, Freiburg) will talk about "COVID-19 and CD8+ T cells"

Newsletter 5

News


We are proud to present you the next issue of our newsletter today under the download link
Read more...

( 10 | 28 | 2021 )

TRR179 goes Podcast

News


In the meantime we have two more episodes of our Podcast available.
Read more...

( 10 | 28 | 2021 )

CanHepC and TRR179 exchange program - call for application open

News


CanHepC and the German TRR179 Network are offering the opportunity for one CanHepC trainee and one student from the German TRR179 Hepatitis Network to do a 2-6 months internship with one the of PIs affiliated to the other network.
Read more...

( 10 | 19 | 2021 )

Post-doc position (f/m/d) in the field of antiviral immunology

Jobs


In a DFG-funded project on infection of the liver with hepatitis B viruses, we are characterizing the immune determinants for control of infection vs failure to control of infection. The focus of the project is on virus-specific CD8 T cells and the local hepatic regulation of their effector functions through environmental and cytokine-induced signals. The AG Wohlleber is looking for a Post-doctoral researcher to investigate the regulation and dynamics of CD8 T cell immunity and identify mechanisms or pathways that will decide whether an HBV infection will develop into acute or chronic infection.
Read more...

OPEN POSITION for a postdoctoral fellow in the research group of Ralf Bartenschlager at Heidelberg University

Jobs


The Bartenschlager group is studying the interaction between plus-strand RNA viruses such as Dengue and Zika virus, SARS-CoV-2 and Hepatitis C virus and their host cells. One major focus is the cell biology underlying virus – host cell interactions aiming to understand how viruses reprogram cells for robust viral replication with the goal to identify possible drug targets for antiviral therapy.
Read more...

Award winners

News


The Distinguished Award in Hepatitis B Research was presented to Michael Nassal and Stephan Urban. Both gave well-received presentation on their groundbreaking work during the HBV meeting 2021.

( 10 | 15 | 2021 )

TRR179 Thursday Lunch Lecture

10 | 07 | 2021

Events


Prof. Dr. Sabrina Schreiner will be on stage this time.

TRR179 - Seminar Series Heidelberg

09 | 21 | 2021

Events


Konstantin Sparrer, Ulm University, on ‘SARS-CoV-2 vs. Innate Immunity’

Seminar Series FREIBURG

09 | 20 | 2021

Events


Determining the essential functions of distinct pro-survival BCL-2 family members by using gene-swap mice

SAVE THE DATE 30./31.05.2022: Intl. Conference of the TRR179

News


We are delighted to invite you to our International Conference "Viral hepatitis and beyond: from basic science to cure" in Freiburg from May, 30-31, 2022.
Read more...

( 07 | 20 | 2021 )

TRR179 Seminar series Freiburg

07 | 05 | 2021

Events


Dr. Paola FISICARO (Laboratory of Viral Immunopathology, Azienda-Ospedaliero-Universitaria di Parma) will talk about "From transcriptomic to functional characterization of virus-specific CD8 T cells in chronic hepatitis B to identify novel molecular targets for therapeutic T cell reconstitution strategies”.

Hepatitis researcher honored

News




Junior research group leader Dr. Maike Hofmann (TP21) has been honored...
Read more...

( 07 | 02 | 2021 )

TRR179 seminar series Munich

06 | 30 | 2021

Events


Seminar talk given by Prof. Dr. Maura Dandri (UKE Hamburg and DZIF) as guest in Munich on
June 30th 2021 at 03:30 pm about “HBV cccDNA silencing: a key step towards functional cure?“

IRTG-Cafe 02. July 2021

06 | 23 | 2021

Events


IRTG Cafe with Ulrike Protzer
Read more...

TRR179 seminar series

06 | 14 | 2021

Events


Professor Maini (UCL Division of Infection and Immunity, London) will talk about “Rescuing HBV-specific CD8 T cells from the tolerogenic liver niche“

TRR179 Seminar series

05 | 18 | 2021

Events


Dr. Paul Ahlquist (University of Wisconsin-Madison, USA) will talk about "Mechanistic insights from structure-function studies of positive-strand RNA virus replication complexes"

TRR179 goes Podcast

News


We are happy to share our first TRR179 podcast with you!


Enjoy listening!!!
Read more...

( 05 | 12 | 2021 )

CONGRATULATION

News


NEW graduate school funded by DFG
Read more...

( 05 | 11 | 2021 )

TRR179 - seminar series Heidelberg

04 | 20 | 2021

Events


Our next guest, Dr. Volker Thiel will talk about "SARS-CoV2: From Genome to Function" online on Tuesday, April 20 at 17:15.
We are looking forward to get the latest information of his research findings.

Thursday Lunch Talk

04 | 15 | 2021

Events


Prof. Dr. Prof. Dr. Adelheid Cerwenka (TP07) will talk about "TNK cells and anti-viral immunity"

Seminar Series Heidelberg

04 | 01 | 2021

Events


Dr. Florian Krammer (Mount Sinai Hospital, New York, USA)
‘Antibody responses to SARS-CoV-2 infection and vaccination’

Virtual Meeting

TRR179 - Online Seminar

04 | 01 | 2021

Events


Our guest, Dr. John Schoggins from the University of Texas Southwestern Medical Center (Dallas, USA) will talk about "Host-based antiviral mechanisms targeting coronavirus and flavivirus"

Thursday Lunch lecture

03 | 18 | 2021

Events


Prof. Dr. Dirk Grimm (TP18) will talk about "The fast and the curious - high-throughput interrogation of viral vector libraries in vitro and in vivo"

IRTG Cafe - Online

03 | 12 | 2021

Events


TRR179 project leader (TP20) Maike Hofmann will talk about her career and the compatibility of work and family...especially in rough pandemic times!

TRR179: A collaborative research network on hepatitis virus persistence and antiviral immunity

03 | 03 | 2021

Events


Ralf Bartenschlager will introduce our TRR179 to our collaborative research partners of the SFB "Jak-Stat Monarchies" in Vienna.

New cooperation

News


We are happy to announce our new cooperation with the Austrian SFB "JAK-STAT Monarchies"
Read more...

( 02 | 25 | 2021 )

CANCELLED: TRR179 - Seminar

02 | 16 | 2021

Events


CANNCELLED:
Dr. John Schoggins
"Host-based antiviral mechanisms targeting coronavirus and flavivirus"
Read more...

Kolloquium 2020 Immunity and Infection

02 | 15 | 2021

Events


Prof. Dr. Lars Engstrand of the Department of Microbiology, Tumor and Cell Biology (Karolinska Institute, Sweden) will talk about
"Studies of the human microbiome in health and disease"

IRTG Cafe

02 | 05 | 2021

Events


IRTG Cafe with Ursula Klingmüller
Read more...

Thursday Lunch Lecture

02 | 04 | 2021

Events


Prof Dr. Andreas Pichlmair, TP11 will talk about "Viruses and their nucleic acids: better get rid of them - but how?"

BEIJERINCK VIROLOGY PRIZE FOR RESEARCH ON HEPATITIS C

News


We are happy to announce that Ralf Bartenschlager, who is speaker of the TRR179, received the Beijerinck Virology Prize 2021

( 01 | 29 | 2021 )

IRTG Cafe 29.01.2021

01 | 29 | 2021

Events


The next IRTG Cafe will take place on Jan. 29th with Julija Miller, CRA at iOMEDICO
Read more...

Preise der deutschen Leberstiftung

News


Aktuelle Ausschreibungen
Read more...

( 01 | 15 | 2021 )

Thursday Lunch Talk

01 | 07 | 2021

Events


Prof. Dr. Percy A. Knolle (TP05) will talk about "Controlling T cell immunity in the liver – the famous and unknowns" this time - as before online of course.
Read more...

DFG - Für das Wissen entschieden

News


Mit “DFG2020 – Für das Wissen entscheiden” will die DFG ihre Überzeugung für eine freie und erkenntnisgeleitete Forschung in die Gesellschaft tragen. Den Anlass gab die Gründung der Vorgängerorganisation der DFG, der “Notgemeinschaft der Deutschen Wissenschaft”, im Jahr 1920. Unter dem Claim #fürdasWissen haben wir 2020 Gründe gesammelt, warum wir uns für das Wissen und die Wissenschaft entscheiden.

( 12 | 29 | 2020 )

TRR179 - IRTG Café - ONLINE

12 | 18 | 2020

Events




Insights into the career of P. Wimmer

Thursday Lunch Talk

12 | 17 | 2020

Events


PD Dr. Tobias Böttler (TP04) talks about "Clinical courses of acute and chronic viral hepatitis"

Hepatitis-D Mega-Deal for a drug "Made in Heidelberg"

News


A discovery by Heidelberg virologist Stephan Urban is worth billions.
Read more...

( 12 | 15 | 2020 )

Kick off Meeting

11 | 20 | 2020

Events


The Kick off meeting of the TRR179 for the second funding period took place ONLINE on 16./17.11.2020.
Read more...

Highly cited researchers

News


Recognizing the most influential researchers 2020
Read more...

( 11 | 19 | 2020 )

Thursday Lunch Talk

11 | 05 | 2020

Events


We start our new "Thursday Lunch talk series"
Read more...

TRR179 - IRTG Café - ONLINE

10 | 23 | 2020

Events


Career pathes and more...interactivity highly requested on Oct 23 from 12:00 - 14:00h!
Read more...

Seminar series in Heidelberg

10 | 20 | 2020

Events


RNA modifications at the virus-host interface
Read more...

Seminar Series - ONLINE - Oct. 19, 2020, 16:00h

10 | 19 | 2020

Events


Biochemical characterisation of endogenous human BAFF and APRIL
Read more...

Wegbereiter für Therapien

News


IRTG Kick off meeting

News




IRTG Kick off meeting for all students of the TRR179 took place as web conference on August 27th, 2020.
Read more...

( 08 | 26 | 2020 )

Neues Medikament zugelassen

News


In der nano Sendung des ZDF vom 20.08.2020 sehen Sie ab Minute 9:40min einen Beitrag von unserem TP-Projektleiter S. Urban zum Thema "Das Hepatitis D-Virus aussperren"
Read more...

( 08 | 21 | 2020 )

Leopoldina - Freiburg

News


Prof. Dr. Robert Thimme was appointed to the National Academy of Sciences, the Leopoldina. This election is considered one of the highest awards for researchers in Germany.
Read more...

( 08 | 13 | 2020 )

OPEN POSITION for a PhD student "Dynamics of hepatitis B virus morphogenesis and its alterations during persistent infection"

Jobs




An open position for a PhD student to analyse the dynamics of hepatitis B virus morphogenesis and its alterations during persistent infection is offered in the Department of Infectious Diseases, Molecular Virology in Heidelberg. We propose that HBV particles are subject to defined ultrastructural dynamics with a series of thermodynamically driven, temporally and spatially regulated events during particle morphogenesis. In this project, we aim at a detailed characterization of nucleocapsids containing the authentic replication complex by biochemical and structural biology methods in the frame of the TRR179.
More details
Read more...

Hepcludex approved

News


In Heidelberg, scientists spent decades researching an active substance against hepatitis D. Now the drug has been approved by the European Commission.This could give hope to millions of infected people. The leading researchers in this field is Prof. S. Urban, one of our project leaders in the TRR179.
Congratulations!

( 08 | 01 | 2020 )

EMBO announces newest elected members

News




EMBO has bestowed upon 63 leading scientists the lifetime honour of EMBO Membership in recognition of their remarkable achievements in the life sciences, it was announced today. “The new Members have contributed to the success of research in the life sciences in Europe and around the world,” said EMBO Director Maria Leptin. “As EMBO Members they can help to shape the future through EMBO’s work to support talented researchers, bring ideas together, and promote an international research environment conducive to excellent science.” One of the new elected EMBO members is Ursula Klingmüller (TP10)

( 07 | 07 | 2020 )

Second Funding Period TRR179

News


We are happy to announce that the TRR179 is beeing funded for another four year periode from July 1st , 2020 on. Stay tuned about the latest research results of our consortium here!!

( 07 | 01 | 2020 )

HIF-1α slows down NK cells

News


Adelheid Cerwenka demonstrated that extended inhibition of HIF-1α in mouse our human NK cells unleashes potent NK cell effector functions (Ni et al., Immunity 2020).
Read more...

( 05 | 26 | 2020 )

ERC Proof-of-concept grant for Mathias Heikenwälder

News


We are happy to announce that Mathias Heikenwälder received the prestigous ERC grant "Proof-of-concept".
Read more...

( 05 | 12 | 2020 )

Hepatitis B: New therapeutic approach

News


Ulrike Protzer, Percy Knolle, Mathias Heikenwälder and Dirk Grimm, all members of the TRR179, were able to show that in both models of HBV infection, mice that express hepatocyte-specific small hairpin RNAs or that were given subcutaneous injections of siRNAs had reduced levels of HBV antigens, HBV replication, and viremia compared to mice given control RNAs.
Read more...

( 02 | 10 | 2020 )

MEDIZIN AM ABEND - Hepatitis virus infections of the liver - the silent epidemic

02 | 10 | 2020

Events


Ralf Bartenschlager, who is speaker of the TRR179 and project leader of TP09 will give a public lecture on 12 February 2020 as part of the "Medizin am Abend" series (large lecture hall of the Kopfklinik, Im Neuenheimer Feld 400, starting at 7 pm).
Read more...

PRINCE MAHIDOL AWARD 2019 FOR RALF BARTENSCHLAGER

News


We are happy to announce that Ralf Bartenschlager, who is speaker of the TRR179, received the Prince Mahidol Award in the field of medicine.
Read more...

( 02 | 10 | 2020 )

TALK OF THOMAS PIETSCHMAN IN HEIDELBERG

02 | 10 | 2020

Events


Thomas Pietschmann will be in Heidelberg on Tuesday, February 18th talking on „Heterogeneity and plasticity: Keys for HCV vaccine research?“
Read more...

TALK OF ELEONORE BARNES IN MUNICH

01 | 07 | 2020

Events


Eleonore Barnes will be in Munich on 13.01.2020 talking on "The development of candidate vaccines for HBV immunotherapy-with lessons from HCV"
Read more...

Three "Highly cited researchers" in 2019

News


In 2019 we are happy to announce that three project leaders of the TRR179 appeared on the list of "Highly Cited Researchers". This international evaluation names researchers whose publications in their respective fields - a total of 21 disciplines in the natural, life and social sciences - have been cited most frequently worldwide or have produced outstanding publications across several disciplines.
Read more...

( 11 | 22 | 2019 )

TRR179 was part of the Night of Research in Heidelberg 2019

News


Together with the TRR209 "Liver Cancer", the SFB1129 and the SPP1923 we participated in the Night of Research in Heidelberg on Friday, 27.09.2019.
Read more...

( 10 | 25 | 2019 )

Ralf Bartenschlager was awarded with the Heinrich-Pette-Lecture

News


On September 12, 2019, Prof. Ralf Bartenschlager, winner of this year's Heinrich Pette Lecture, held his honorary lecture at the HPI entitled "Hepatitis C virus and its relatives: Quite similar, but so different".
Read more...

( 09 | 27 | 2019 )

Science Night in Heidelberg on Friday, September 27th 2019

09 | 27 | 2019

Events


The TRR179 will participate also this year participate in the Science Night in Heidelberg.
Read more...