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TRR 179


News

Latest / recent publications.

Events

Invited speakers, symposia, retreat, coaching.

Jobs

Open positions.

TRR - Retreat 2025

07 | 16 | 2025

Events


We are already looking forward to our annual retreat, this year taking place on July 16./17. at the well known location of the Evangelische Akademie in Bad Boll.

TRR179 Thursday Lunch Lecture

05 | 08 | 2025

Events


Prof. Dr. Volker Lohmann, TRR179 TP17 will speak on
"Evolution of highly replicating HCV variants and their contribution to pathogenesis and persistence"

Seminar Series Munich

05 | 05 | 2025

Events


Benedikt Strunz, MD PhD
Center for Infectious Medicine (CIM) 14186 Huddinge/Stockholm

will speak on

The effect of immunosuppression on circulating and tissue-resident immune cells

Seminar Series Heidelberg

04 | 15 | 2025

Events


Friedemann Weber (Gießen) will talk about "Anti-interferon strategies of phleboviruses"

Joint DGI-DZIF Poster Prize 2025

News


The Best Poster prize has been awarded to Ecem Sekban, PhD student in project TP18 in München 2025. Congrats!

( 04 | 09 | 2025 )

Best oral communication Prize 2025

News


Sarah Prallet (TP22) again won a prize, this time for the best oral presentation at the RNH25 Réseau National Hépatites, réunion annuelle AC42, at Institute Pasteur in Paris for her presentation on "Human intestinal organoids to study the stem cell niche as a potential reservoir for HEV infections"

( 04 | 09 | 2025 )

Joint DGI-DZIF poster prize 2025

News


Best Poster prize has been awarded to Niclas Maier, the Master student in project TP22 in München 2025. Congrats!

( 04 | 09 | 2025 )

Young Scientist Award Best Poster

News


Sarah Prallet (TP22) was awarded with the Poster Prize during the Eibssee meeting. We are very proud and send our congratulations.

( 04 | 09 | 2025 )

Seminar on Infection and Immunity (@TUM)

04 | 09 | 2025

Events


Paul Klenerman from Oxford will talk about „MAIT cells - killing with kindness“
Read more...

Thursday Lunch Lecture

04 | 03 | 2025

Events


Dr. Anna Kosinska (TP18, TUM) will speak on "Identifying the factors preventing effective therapeutic hepatitis B vaccination"

TRR179 Seminar series Heidelberg

03 | 17 | 2025

Events


Caroline Goujon (Montpellier) will talk about" Intrinsic and innate immune defenses against RNA viruses"

TRR179 thursday Lunch lecture

03 | 06 | 2025

Events


Dr. Stefan Seitz (TP23, HD) will talk about "Data-Driven Virus Discovery to identify emerging hepatitis viruses & high-risk candidates for spillover into humans"

Seminar Series Heidelberg

02 | 18 | 2025

Events


Thomas Baumert (Strasbourg) will talk about "Claudin-1: from HCV entry to discovery of novel therapeutics for fibrosis and cancer"
Read more...

Seminar series heidelberg

02 | 03 | 2025

Events


One of our former project leaders, Steeve Boulant (TP22), now at the University of Florida, will talk about "Impact of the intestinal hypoxic environment on host / enteric pathogen interactions: a viral and eukaryotic parasite perspective".

Thursday Lunch lecture

01 | 30 | 2025

Events


Ralf Bartenschlager (TP09, Heidelberg)
will speak on
"Host cell factors associated with HBV-(derived) particles and their role in the viral life cycle"

GRK2727 Conference 23./24.01.2025 (Heidelberg)

01 | 23 | 2025

Events


The international conference of GRK2727 will take place from 23. - 24.01.2025 in DKFZ/Heidelberg. They have put together an exciting program covering several aspects of innate immunity. More details will follow.

TRR179 - Seminar Series Heidelberg

12 | 18 | 2024

Events


Dr. Marc Windisch (Virology Research, Assembly Biosciences Inc., South San Francisco, USA) will talk about:

"From bench-to-bedside: Development of a novel orally bioavailable, small-molecule drug candidate for the treatment of hepatitis D virus infections."
"Towards the development of an orally bioavailable and liver-focused interferon-alpha receptor 2 agonist for the cure of chronic hepatitis B and D virus."

Each topic will be covered for 20 minutes

TRR179 goes Podcast

News


TRR179 about "Attenuated effector T cells and chronic HBV infection"
Read more...

( 12 | 16 | 2024 )

TRR179 - Seminar Series Munich

12 | 09 | 2024

Events


We are happy to invite you to the seminar given by Prof. Lei Wei, PhD (Westlake University in Hangzhou, China) about „The phantom of the opera - A journey with the hepatitis B virus”.

Thursday Lunch Lecture

12 | 05 | 2024

Events


Sabrina Schreiner will speak on "PML integrity & SUMO crosstalk during Virus Infection – Novel therapeutic options"

ERC grant for Anne Schütz, project leader TP23

News


The European Research Council supports innovative projects with Consolidator Grants. We are happy to announce that our project leader Anne Schütz is being funded by the EU with an ERC starting grant for her project "ZoomNMR (Zooming in on small-molecule ligands by magnetic resonance)".
Read more...

( 12 | 03 | 2024 )

Highly cited researchers 2024

News


We are very pleased that two of our project leaders are again among the most highly cited scientists in their field this year: B. Bengsch and R. Bartenschlager. Ralf for the twelfth time in a row. Congratulations!

( 11 | 21 | 2024 )

TRR179 @ the open house

11 | 17 | 2024

Events


We are happy that we could inform very many interested people about hepatitis research and the consortium during the open house day at the dkfz! It was fun feeling the curiosity and openness of the visitors.

Thursday Lunch Lecture

11 | 14 | 2024

Events


Today´s Lunch Lecture will be held by Dr. Dr. Katrin Böttcher (TUM r.I., TP25) about "Novel cellular players in antiviral immunity? The role of innate-like T cells for viral infections of the liver."

TRR179 - Retreat 2024

10 | 28 | 2024

Events


Annual internal retreat 2024 on Oct. 28./29., 2024 in Bad Boll.

Thursday Lunch Lecture

10 | 10 | 2024

Events


"Basics of liver pathology" by C. Mogler

Seminar series Munich

09 | 23 | 2024

Events


Prof. Dr. Emmanuel Saliba (Helmholtz Institute for RNA-based infection research (HIRI)) will talk about „Identifying host vulnerabilities to infections using single-cell genomics”

Thursday Lunch Lecture

09 | 05 | 2024

Events


Dr. Marco Binder from project TP11 (DKFZ Heidelberg) gives a talk on "Being prepared for the next strike – only primed cells respond fast enough".
As usual the talk will be recorded and available afterwards.

Press release @TUM

News


Check out...
Read more...

( 07 | 30 | 2024 )

TRR179 goes Podcast

News


We just published the latest and kind of anniversary edition - the 10. Podcast of the TRR179!!!
In this episode you can learn more about the technologies provided and used by the TRR179.
Read more...

( 07 | 25 | 2024 )

TRR179 Seminar Series Munich

07 | 24 | 2024

Events


On Wednesday, July 24th Prof. Ben Burwitz from Oregon National Primate Research Center, Oregon Health & Science University will talk about "A non-human primate model of HBV infection" at the Institute for Virology at TUM. It is a hybrid event and open for everybody interested.

Thursday Lunch Lecture

07 | 04 | 2024

Events


Prof. Dr. Maike Hofmann (TP20) will talk about "T cell exhaustion and beyond: virus-specific CD8+ T cell responses in chronic viral hepatitis"

Academic Lunch Break 2024

06 | 19 | 2024

Events


Within the frame of the Health + Life Science Alliance Heidelberg Mannheim, R. Bartenschlager (TP09) will talk about "Wie entwickelt man eigentlich eine antivirale Therapie?" during the academic lunch break
Read more...

Gesundheit - Leben - Innovation

06 | 19 | 2024

Events


Die Health + Life Science Alliance Heidelberg Mannheim bietet im Rahmen der Akademischen Mittagspause 2024 Einblicke in die aktuelle Spitzenforschung in
den Lebenswissenschaften, in die Behandlung menschlicher Krankheiten und die wissenschaftlichen Grundlagen für neue Therapien. Der TRR179 ist mit Beiträgen aktiv daran beteiligt.
Read more...

Seminar series Heidelberg

06 | 17 | 2024

Events


On Monday June 17th at 17:15 h
John Schoggins (Dallas, USA) will talk about “Interferon-mediated antiviral strategies in humans, bats, and beyond”

Gesundheit - Leben - Innovation

06 | 05 | 2024

Events


Die Health + Life Science Alliance Heidelberg Mannheim bietet im Rahmen der Akademischen Mittagspause 2024 Einblicke in die aktuelle Spitzenforschung inden Lebenswissenschaften, in die Behandlung menschlicher Krankheiten und die wissenschaftlichen Grundlagen für neue Therapien. Der TRR179 ist mit Beiträgen aktiv daran beteiligt.

Third funding period granted

News


We are happy to announce that our TRR179 has been approved for another, final funding phase of 4 years by the DFG!!

( 05 | 31 | 2024 )

TRR179 Seminar Series Munich

04 | 15 | 2024

Events


by Prof. Dr. Carolina Boni (Dept of Medicine & Surgery, Parma) will talk about „Can CD8 T cell analysis define patient propensity to achieve HBV cure?”
Read more...

Ju-FORUM Congress

04 | 05 | 2024

Events


The visit of the Center for Infectious Diseases was part of this year's JuFORUM Congress in Heidelberg.
Read more...

THURSDAY LUNCH LECTURE

04 | 04 | 2024

Events


Dr. Immanuel Andrä (Z02) from the Institute for Medical Microbiology, Immunology und Hygiene at TUM will talk about "Handling rare cells with FACS purification: high-throughput options for single cell assay readouts and data – applications, limitations and caveats"

DZIF/GfV AWARD 2024

News


We are very happy and proud to announce, that our recently graduated Alumni Ombretta Colasanti (TP17/ V. Lohmann) was awarded with the annual DZIF/GfV Award 2024. The award ceremony took place on 26 March at the annual GfV conference in Vienna.
CONGRATS, Ombretta!

( 03 | 27 | 2024 )

THURSDAY LUNCH LECTURE

03 | 07 | 2024

Events


Prof. Dr. Christoph Neumann-Haefelin (TP02, Department of Medicine II, University of Freiburg) will speak on "Hepatitis Delta: Impact of current and upcoming antiviral therapies on the immune response"

Joint seminar series Freiburg - Heidelberg

02 | 26 | 2024

Events


"Transcriptional regulation of T cell activation states" by Dr. Joris van der Veeken
Read more...

Therapeutic vaccine Ther-Vac-B

News


The novel therapeutic vaccine TherVacB to combat chronic hepatitis B has reached the first clinical trial phase. In the phase 1a clinical trial, the safety and immunogenicity of the novel vaccine candidate will be investigated in healthy volunteers.
Read more...

( 02 | 23 | 2024 )

TRR179 Seminar Series Munich

02 | 12 | 2024

Events


Prof. Dr. Julian Grünewald (TUM) will speak on "Engineering CRISPR technologies for research and therapeutic applications"
Read more...

TRR179 Seminar Series Munich

02 | 05 | 2024

Events


Dr. Celia P. Martinez-Jimenez
Helmholtz Pioneer Campus/ Helmholtz Zentrum München
will speak on
Ageing and metabolic function: Dissecting one cell at a time
Read more...

Thursday Lunch Lecture

02 | 01 | 2024

Events


Dr. Jochen Wettengel (Technical University of Munich, Institute of Virology)
will speak on: "Recombinant Hepatitis B Virus particles"

IRTG Café

01 | 26 | 2024

Events


Prof. Dr. Anne Schütz, Ludwig-Maximilians-Universität München
"Career pathway and more"
Read more...

TRR179 goes Podcast

News


We just published the latest episode of our Podcast!
Read more...

( 12 | 28 | 2023 )

Seminar series Munich

12 | 21 | 2023

Events


Dr. Lena Allweiss (University Medical Center Hamburg-Eppendorf) wioll give a talk about
“Epigenetic regulation of HBV cccDNA during antiviral treatment in humanized mice”.

IRTG-Café

12 | 15 | 2023

Events


Jun. Prof. Konstantin Sparrer, Ulm University, "Career pathway and more"
Read more...

Thursday Lunch Lecture

12 | 07 | 2023

Events


PD Dr. Dirk Wohlleber (TP13, Institute of Molecular Immunology and Experimental Oncology TUM) will talk about "Restoration of antiviral immunity during chronic liver infection"

Bavarian m4 Award for Ther-Vac-B

News


TherVacB is a spin-off for the development of a therapeutic hepatitis B vaccination in which our project leaders U. Protzer (TP14, TP18) and P. Knolle (TP05) were strongly involved in its foundation
Read more...

( 12 | 01 | 2023 )

Joint seminar Freiburg

11 | 27 | 2023

Events


Prof Dr. Ping-Chih Ho (Ludwig Institute for Cancer Research, Lausanne Switzerland) will talke about"
Listen to Heme. You are exhausted"

Dies academicus 2023: University of Basel confers honorary doctorates

News


Prof. Dr. Stephan Urban (TP15) was awarded an honorary doctorate from the Faculty of Medicine of the University Basel for his groundbreaking discoveries in the field of molecular virology of hepatitis B and hepatitis D viruses, which led to the development of the first drug against chronic hepatitis D.

( 11 | 22 | 2023 )

Highly cited researchers 2023

News


The list of “Highly Cited Researchers” that has just appeared. Our speaker Prof. Dr Ralf Bartenschlager (cross-field) is on the list of “Highly Cited Researchers” for the eleventh time in a row. Also project leaders Mathias Heikenwälder (TP06) and Bertram Bengsch (TP21) are again on the list of highly cited researchers. Congratulations!
Read more...

( 11 | 20 | 2023 )

THURSDAY LUNCH LECTURE

11 | 02 | 2023

Events


Dr. Anna Kosinska (Technical University of Munich, Institute of Virology) will speak on "Therapeutic vaccination against chronic hepatitis B"

SEMINAR SERIES FREIBURG

10 | 30 | 2023

Events


PD Dr. Dirk Wohlleber (Institute of Molecular Immunology and Experimental Oncology, TU Munich) will speak on "Control of antiviral CD8 T cell function in the liver"

Lab rotation scholarship

10 | 26 | 2023

Events


Sarah Prallet, TRR179 TP22 visits Dr. Senjuti Saha at the Child Health Research Foundation (CHRF) in Dhaka, Bangladesh

THURSDAY LUNCH LECTURE

10 | 05 | 2023

Events


The next Thursday Lunch Lecture will be given by Jochen Wettengel (TP14) about "Recombinant Hepatitis B Virus particles".
We are looking forward to an informative lunch break and many participants.

Flow School 2023

10 | 02 | 2023

Events


CRC TRR179 IRTG Workshop Advanced Flow Cytometry and Cell Sorting/Flow School 2023, TU Munich, October 2023, 9 - 13, Munich

Seminar Series Munich

09 | 25 | 2023

Events


Prof. Schultz form LIMES-Institute at the University of Bonn will talk about " Single Cell Level Immune Analysis: Are we ready for clinical applications?"

DZIF AWARD 2023

News


This year, the German Center for Infection Research (DZIF) honors the virologist Prof. Ralf Bartenschlager and speaker of our consortium (and PI TP09, Heidelberg) for his scientific achievements with the DZIF Award for Translational Infection Research. Congratulations!

( 09 | 25 | 2023 )

DGFZ Poster award

News


We have some happy news, Frances Winkler from TP21 won the poster award at the DGFZ annual meeting 2023 for her paper "Enolase represents a metabolic checkpoint controlling the differential exhaustion programs of hepatitis virus-specific CD8+ T cells." Congratulations!

( 09 | 22 | 2023 )

WORLD HEPATITS DAY TODAY

News




On the occasion of World Hepatitis Day, our Associate Young Scientist Shirin Nkonglo gave an interview on ZDF heute. Important to draw attention to this day!
Read more...

( 07 | 28 | 2023 )

GRK2727 Vienna Workshop 2023

07 | 10 | 2023

Events


We are actively contributing to the common workshop organized by our cooperation partners GRK 2727 and the JakStat consortium taking place on July 10-12th, 2023 ion Vienna.

Thursday Lunch Lecture

07 | 06 | 2023

Events


Dr. Maike Hofmann, TRR179 TP20 (Department of Medicine II, Gastroenterology, Hepatology, Endocrinology and Infectious Diseases, Medical Center University of Freiburg) will speak on "T cell exhaustion and memory - lessons from chronic viral hepatitis". It´s worth joining!

Science Splash

07 | 05 | 2023

Events


The Alliance Science Splash allows you to present your research, foster new collaborations, and get inspired by three excellent keynote speakers, amongst them project leader of TP16, S. Urban (HD)

Seminar Series Freiburg

06 | 28 | 2023

Events


Prof. Dr. Jacques Neefjes (Department of Cell and Chemical Biology, University Medical Center, Leiden, Netherlands) will speak on

"How to detoxify doxorubicin to dramatically improve overall survival of AML patients"

TRR179 seminar series Freiburg

06 | 26 | 2023

Events


Prof. Dr. Daniel Pinschewer (University of Basel, Department of Biomedicine, Basel, Switzerland) will be our guest. The title will be announced soon.
The colloquium is open to anyone interested.

TRR179 Seminar Series - Heidelberg

06 | 20 | 2023

Events


Eike Steinmann (Ruhr-University Bochum) will give a talk on ‘Molecular Mechanisms of Hepatitis E Virus Replication’.
The seminar will take in hybrid format.

TRR179 - Seminar Series Freiburg

06 | 19 | 2023

Events


Prof. Dr. Yohei Yamauchi will speak on "Decoding the Molecular Dance between Influenza Virus and Host Cells"
Guests are welcome!
Read more...

IRTG Cafe

06 | 02 | 2023

Events


This time, Dr. Katrin Böttcher, MD, PhD, who is principal investigator and research group leader at Klinikum rechts der Isar, Technical University of Munich, will talk about her career path and more!

Thursday Lunch Lecture

06 | 01 | 2023

Events


Dr. Immanuel Andrä (Z03, Flow Cytometry Unit CyTUM MIH, Institute for Medical Microbiology, Immunology und Hygiene, Technical Universtity Munich) will speak on "FACS based high-throughput cell isolation methods for single cell assay readouts and data – options, limitations and caveats"

Thursday Lunch Lecture

05 | 04 | 2023

Events


Prof. Dr. Tobias Böttler, TRR179 TP04 (Department of Medicine II, Gastroenterology, Hepatology, Endocrinology and Infectious Diseases, Freiburg) will speak about "Clinical courses of acute and chronic viral hepatitis"

Seminar series Munich

05 | 01 | 2023

Events


Todays seminar will be given by Prof. Christian Lange about „Inflammation in liver cirrhosis : driver of failed liver regeneration and impaired cellular immunity”.
Read more...

SciencePub

04 | 25 | 2023

Events


Highly recommended!
Read more...

Science Pub

04 | 25 | 2023

Events


We are happy to announce that M. Binder an L. Dao Thi will talk about "Viral Hepatitis and Beyond - Basic Research and Cure" in the Cafe Leitstelle in a relaxed atmosphere. Everybody is welcome to come over and have a beer.
Read more...

Gender seminar

04 | 24 | 2023

Events




We will have a follow up seminar by Karin Greiner-Simank on "Profit by difference", also known as Arrogance training.
Read more...

TRR179 Goes Podcast

News


The already sevens episode of our podcast is dealing with "Therapeutic Vaccination of HBV". Enjoy listening: HERE

( 04 | 13 | 2023 )

IRTG Cafe

03 | 17 | 2023

Events


Volker Lohmann, PI of the TRR179, TP17 and Deputy Head of the Department "MOLECULAR VIROLOGY“, Department of Infectious Diseases, CIID, at Heidelberg University Hospital, will talk in relaxed atmosphere about his career and more!

„How I became a virologist“

Thursday Lunch Lecture

03 | 16 | 2023

Events


T cell exhaustion and memory- lessons from chronic viral hepatitis
Read more...

TRR179 Thursday Lunch Lectures

03 | 02 | 2023

Events


Prof. Dr. Volker Lohmann , TRR179 TP17 (Department of Infectious Diseases, Molecular Virology, CIID Heidelberg)
will speak on "Determinants of HCV immune response and pathogenesis"

TR179 Seminar Series Munich

02 | 09 | 2023

Events


Dr. Carl-Philipp Hackstein (University of Oxford) will talk about "Chronic hepatic injury, microbes and cytokines: Impact on adaptive immunity in the liver and beyond."

Thursday Lunch Lecture

02 | 02 | 2023

Events


Our speaker Ralf Bartenschlager will talk about "Commonalities and Differences between hepatitis B and hepatitis C virus"

TRR179 in the media

News


TRR179 conducts public relations work to bring the research topic closer to the general public.
We are happy to share a the broadcast with U. Protzer of the Roman Herzog Institute! "How will we control infectious diseases in the future?"


Enjoy watching!!!

( 01 | 26 | 2023 )

TRR179 Seminar series Freiburg

01 | 24 | 2023

Events


Dr. Upkar Gill (Barts Liver Centre in London) will give a talk about "Probing the immune response to optimise treatment strategies for Chronic Hepatitis B"

IRTG Cafe

12 | 02 | 2022

Events


TRR179 Alumni Andreas Oswald is sharing his experience.
Read more...

Thursday Lunch Lectures

12 | 01 | 2022

Events


Studying HEV transmission along the gut liver axis
Read more...

TRR179 goes Podcast

News


In today's episode, our PhD- and MD-students present the integrated graduate school of the TRR. A very varied and informative compilation. Enjoy listening!
Read more...

( 12 | 01 | 2022 )

HIGHLY CITED RESEARCHERS 2022

News


The list of “Highly Cited Researchers” that has just appeared. Our speaker Prof. Dr Ralf Bartenschlager (cross-field) is on the list of “Highly Cited Researchers” for the tenth time in a row. Also project leader Mathias Heikenwälder (TO06) is on the list of highly cited researchers. Congratulations!
Read more...

( 11 | 29 | 2022 )

Baruch S. Blumberg Preis 2023

News


Stephan Urban erhält den Baruch S. Blumberg Preis 2023
Read more...

( 11 | 18 | 2022 )

Thursday Lunch Lecture

11 | 10 | 2022

Events


Marcus Rosenblatt (TP10) will talk about "From Data Alignment over Parameter Estimation to Model Selection and Predictions - The Daily Life as a Modeler" in our Thursday Lunch Lecture.

TRR179 - Seminar Series Freiburg

11 | 07 | 2022

Events


"Insights from a subgenome-resolved SARS-CoV-2 RNA interactome"
Read more...

Thursday Lunch Lecture

11 | 03 | 2022

Events




Jens Timmer (TP10) will give insights into the HBV infection cycle and cross talk to host cell response

CANHEPC AND TRR179 EXCHANGE PROGRAM - CALL FOR APPLICATION OPEN

News


CanHepC and the German TRR179 Network are again offering the opportunity for one CanHepC trainee and one student from the German TRR179 Hepatitis Network to do a 2-6 months internship with one the of PIs affiliated to the other network.
Read more...

( 10 | 21 | 2022 )

TRR179 Seminar Series - Freiburg

09 | 19 | 2022

Events


Dr. Stefan Jordan, the Head of the Laboratory of Microbiology, Metabolism and Inflammation (LoMMI), Institute of Microbiology, Infectious Diseases and Immunology at the Charité – Universitätsmedizin in Berlin will speak on "Microbiome, Metabolism, Inflammation: Dietary Energy in Immunoregulation and Inflammatory Disease". You are welcome to join in the Hörsaal Virologie, Haus C, EG, Hermann-Herder-Str. 11, Freiburg.

Cooperation started GRK2727

News


We are happy to announce a new cooperation partner of our consortium, the GRK 2727 InCheck „Innate Immune Checkpoints in Cancer and Tissue Damage"!
Read more...

( 09 | 01 | 2022 )

TRR179 Seminar

08 | 09 | 2022

Events


Prof. Dr. Volker Lohmann (University of Heidelberg, Department of Infectious Diseases, Molecular Virology, CIID and TP17) will talk about "Assessing the RNA replication fitness of HCV isolates in cell culture: The return of the ISDR” in the lecture hall in Freiburg (Int. medicine)

World Hepatitis Day

News


World Hepatitis Day (WHD) takes places every year on 28 July bringing the world together under a single theme to raise awareness of the global burden of viral hepatitis and to influence real change. In 2022 the theme is ‘I Can’t Wait’. It’s also a day to celebrate the progress we have made and to meet the current challenges and an opportunity for us to jointly facilitate prevention, diagnosis and treatment.

( 07 | 28 | 2022 )