Elimination vs. persistence of hepatitis virus infection

TP01

Fate and function of scarred virus-specific T cells in chronic viral hepatitis

TP02

Virus-specific CD8+ T cell responses in hepatitis B/D virus co-infection: mechanisms of failure and strategies for restoration

TP04

Regulation of virus-specific CD4 T helper cell responses in viral hepatitis

TP05

Reconstitution of potent antiviral CD8 T cell immunity to achieve elimination of infected hepatocytes during persistent HBV infection

TP07

Dissecting NK cell-reactivity against hepatitis virus infection

TP09

Control of hepatitis virus infection by the interferon system and by exploiting virus – host cell interactions

TP11

Effects of constitutive cytokine signalling on tissue homeostasis and liver cell-intrinsic responsiveness to hepatitis virus infection

TP13

Dynamics of anti-viral immunity against viral infection of the liver

TP14

Establishment and fate of hepatitis B virus cccDNA

TP15

Characterization of hepatitis D virus cell division-mediated spread and interference through innate and adaptive immune responses.

TP16

Determinants, dynamics and diversity of SUMO/PML nuclear bodies in the control of hepatitis B virus infection and cccDNA

TP17

Contribution of innate immune responses to persistence versus clearance of hepatitis C and hepatitis A virus infections

TP18

Reconstitution of antiviral immunity and elimination of persisting hepatitis B virus infection

TP19

Integrated Research Training Group “Immunovirology”

TP20

Stem-like CD8+ T cells in chronic viral hepatitis: maintenance and targeting of CD8+ T cell immunity

TP21

Metabolic regulation of the virus-specific T cell response in viral hepatitis

TP22

From genotype to phenotype: Towards a better understanding of hepatitis E virus tropism and chronic infection

TP23

The dynamics of hepatitis B virus morphogenesis and its relevance to persistent infection.

TP24

Functional analysis of molecular perturbations induced by Hepatitis B and D virus infection

TP25

Metabolic regulation of mucosal-associated invariant T (MAIT) cell anti-viral function against hepatitis B virus infection

Z01

Central tasks of the transregional collaborative research centre 179

Z02

High-resolution multi-parametric cell and tissue analysis

Z03

Experimental and computational single-cell analysis with high spatial resolution

▲