Scientific Vita
Publi­cations
Con­tact

Prof. Dr.

Sabrina Schreiner

Academic Education and University Degrees

2014
Habilitation in Virology, University of Hamburg (mentor: Prof. Dr.Thomas Dobner), Germany
2006 - 2010
Ph.D. thesis, University of Hamburg, Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Germany, supervised by Prof. Dr. Thomas Dobner, University of Hamburg, Germany
2005 - 2006
Diploma work, Biology, University Hospital Regensburg, Institute for Microbiology and Hygiene, Germany, supervised by Prof. Thomas Dobner, University Hospital Regensburg, Germany
2001 - 2006
Study of Biology at Regensburg University, Germany

Employment

starting July 2023
W3 Professor, “Schwerpunkt Molekulare Virologie” Institute of Virology, University Hospital Freiburg, Freiburg, Germany
since Oct 2020-ongoing
W2 Professor, “Viral replication in Host Chromatin”, RESIST Excellence Cluster, Institute of Virology, Hannover Medical School (MHH), Hannover, Germany
Since 01/2015
Group leader at the Institute for Virology, TU Munich, Germany
2010 - 2014
Postdoc and group leader at the Department of Molecular Virology, Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Germany
1. Hofmann S, Plank V, Groitl P, Skvorc N, Hofmann K, Ko C, Zimmermann P, Bruss V, Stadler D, Carpentier A, Rezk S, Nassal M, Protzer U, Schreiner S. (2023) SUMO mdification of HBV core mediates nuclear entry, PML association and efficinet cccDNA formation. Microbiol Spectr. 18;e0044623. doi: 10.1128/spectrum.00446-23.
2. Weiß C, Göttig L, Stubbe M, Hofmann S, Stadler D, Carpentier A, Protzer U, Schreiner S. (2023) Apobec3A deamination 1 capacity antagonizes efficient human adenovirus replication and gene expression. mBio. 8;e0347822. doi: 10.1128/mbio.03478-22.
3. Mai J, Stubbe M, Hofmann S, Masser S, Dobner T, Boutell C, Groitl P, Schreiner S. (2022) PML alternative splice products differentially regulate HAdV productive infection. Microbiol Spectr. 10(4):e0078522. doi: 10.1128/spectrum.00785-22.
4. Stubbe M, Mai J, Paulus C, Stubbe HC, Berscheminski J, Karimi M, Hofmann S, Weber E, Hadian K, Hay RT, Groitl P, Dobner T, Nevels M, Schreiner S. (2020) HAdV E2A SUMOylation prevents antiviral response promoted by host PML-NB components. mBio. Mar 17;11(2):e00049-20. doi: 10.1128/mBio.00049-20.
5. Hofmann S, Mai J, Masser S, Groitl P, Hermann A, Brack-Werner R, Sternsdorf T, Schreiner S. (2020) ATO (Arsenic Trioxide) effects on PML nuclear bodies reveals antiviral intervention capacity. Adv Sci. 7(8): 1902130. doi: 10.1002/advs.201902130.
6. Müncheberg S, Hay TR, Ip HW, Meyer T, Weiß C, Brenke J, Masser S, Hadian K, Dobner T, Schreiner S. (2018) E1B-55K mediated regulation of RNF4 STUbL promotes HAdV gene expression. J Virol. 3;92(13). doi: 10.1128/JVI.00164-18.
7. Freudenberger N, Hay RT, Groitl P, Dobner T, Schreiner S. (2018) HAdV pV core protein is targeted by the host SUMOylation machinery to pursue essential viral functions. J Virol. 30;92(4). doi: 10.1128/JVI.01451-17.
8. Wimmer P, Berscheminski J, Blanchette P, Groitl P, Branton PE, Hay RT, Dobner T, Schreiner S. (2016). PML isoforms IV and V contribute to adenovirus-mediated oncogenic transformation by functionally inhibiting the tumor suppressor p53. Oncogene. 35(1):69-82. doi: 10.1038/onc.2015.63.
9. Bürck C, Mund A, Berscheminski J, Kieweg L, Müncheberg S, Dobner T*, Schreiner S*. (2015) KAP1 is a host restriction factor that promotes HAdV E1B-55K SUMO modification. J. Virol. 90(2):930-46. doi: 10.1128/JVI.01836-15. *corresponding authors.
10. Berscheminski J, Brun J, Speiseder T, Wimmer P, Ip WH, Terzic M, Dobner T, Schreiner S. (2015) Sp100A is a tumor suppressor that activates p53-dependent transcription and countercats E1A/E1B-55K-mediated transformation. Oncogene. 16;35(24):3178-89. doi: 10.1038/onc.2015.378.
Address
Institute of Virology
Technische Universität München
Ingolstädter Landstrasse 1
85764 Neuherberg
eMail
sabrina.schreiner@tum.de