Attending Physician, Department of Medicine II, University Hospital Freiburg
Scientific Vita
Publications
Contact
Dr.
Hendrik Luxenburger
Since 10/2022
05/2022
Specialist for internal medicine
Since 04/2019
Fellow of the IMM-PACT Program for Clinician Scientists
Since 02/2017
Resident, Department of Internal Medicine II, Gastroenterology, Hepatology, Endocrinology and Infectiology, University Medical Center Freiburg, Germany
09/2020
Experimental MD thesis "Characterization of virus-specific CD8+ T- cell responses in chronic hepatitis C genotype 1 and 4 infection", Department of Internal Medicine II, Albert-Ludwigs-University Freiburg.
09/2007 - 12/2016
Medical studies, Université de Strasbourg/Albert-Ludwigs-University of Freiburg
1. Luxenburger H*, Reeg DB*, Lang-Meli J*, Reinscheid M, Eisner M, Bettinger D, Oberhardt V, Salimi Alizei E, Wild K, Graeser A, Karl V, Sagar, Emmerich F, Klein F, Panning M, Huzly D, Bengsch B, Boettler T, Elling R, Thimme R, Hofmann M, Neumann-Haefelin C. (2023) Boosting compromised SARS-CoV-2-specific immunity with mRNA vaccination in liver transplant recipients. J Hepatol. 78(5):1017-1027. doi: 10.1016/j.jhep.2023.02.007. *equal contribution.2. Reinscheid M*, Luxenburger H*, Karl V*, Graeser A*, Giese S*, Ciminski K*, Reeg DB*, Oberhardt V, Roehlen N, Lang-Meli J, Heim K, Gross N, Baum C, Rieg S, Speer C, Emmerich F, Breisinger S, Steinmann D, Bengsch B, Boettler T, Kochs G, Schwemmle M, Thimme R*, Neumann-Haefelin C*, Hofmann M*. (2022) COVID-19 mRNA booster vaccine induces transient CD8+ T effector cell responses while conserving the memory pool for subsequent reactivation. Nat Commun. 8;13(1):4631. doi: 10.1038/s41467-022-32324-x. *equal contribution.3. Lang-Meli J*, Luxenburger H*, Wild K*, Karl V*, Oberhardt V, Salimi Alizei E, Graeser A, Reinscheid M, Roehlen N, Reeg DB, Giese S, Ciminski K, Götz V, August D, Rieg S, Waller CF, Wengenmayer T, Staudacher D, Huzly D, Bengsch B, Kochs G, Schwemmle M, Emmerich F, Boettler T, Thimme R*, Hofmann M*, Neumann-Haefelin C*. (2022) SARS-CoV-2-specific T-cell epitope repertoire in convalescent and mRNA- vaccinated individuals. Nat Microbiol. 7(5):675-679. doi: 10.1038/s41564-022-01106-y. *equal contribution.4. Oberhardt V*, Luxenburger H*, Kemming J*, Schulien I*, Ciminski K, Giese S, Csernalabics B, Lang-Meli J, Janowska I, Staniek J, Wild K, Basho K, Marinescu MS, Fuchs J, Topfstedt F, Janda A, Sogukpinar O, Hilger H, Stete K, Emmerich F, Bengsch B, Waller CF, Rieg S, Sagar, Boettler T, Zoldan K, Kochs G, Schwemmle M, Rizzi M, Thimme R*, Neumann-Haefelin C*, Hofmann M*. (2021) Rapid and stable mobilization of CD8+ T cells by SARS-CoV-2 mRNA vaccine. Nature. 597(7875):268-273. doi: 10.1038/s41586-021-03841-4. *equal contribution.5. Schulien I*, Kemming J*, Oberhardt V*, Wild K*, Seidel LM*, Killmer S*, Sagar, Daul F, Salvat Lago M, Decker A, Luxenburger H, Binder B, Bettinger D, Sogukpinar O, Rieg S, Panning M, Huzly D, Schwemmle M, Kochs G, Waller CF, Nieters A, Duerschmied D, Emmerich F, Mei HE, Schulz AR, Llewellyn-Lacey S, Price DA, Boettler T*, Bengsch B*, Thimme R*, Hofmann M*, Neumann-Haefelin C*. (2021) Characterization of pre-existing and induced SARS-CoV-2-specific CD8+ T cells. Nat Med. 27(1):78-85. doi: 10.1038/s41591-020-01143-2. *equal contribution.6. Boettler T*, Csernalabics B*, Salié H, Luxenburger H, Wischer L, Salimi Alizei E, Zoldan K, Krimmel L, Bronsert P, Schwabenland M, Prinz M, Mogler C, Neumann-Haefelin C, Thimme R, Hofmann M*, Bengsch B*. (2022) SARS-CoV-2 vaccination can elicit a CD8 T-cell dominant hepatitis. J Hepatol. 77(3):653-659. doi:10.1016/j.jhep.2022.03.040. *equal contribution.7. Luxenburger H*, Graß F*, Baermann J, Boettler T, Marget M, Emmerich F, Panning M, Thimme R, Nitschke K, Neumann-Haefelin C. (2018) Differential virus-specific CD8+ T-cell epitope repertoire in hepatitis C virus genotype 1 versus 4. J Viral Hepat. 25(7):779-790. doi: 10.1111/jvh.12874. *equal contribution.8. Luxenburger H, Neumann-Haefelin C. (2023) Liver-resident CD8+ T cells in viral hepatitis: not always good guys. J Clin Invest. 133(1):e165033. doi: 10.1172/JCI165033. 9. Luxenburger H, Neumann-Haefelin C, Thimme R, Boettler T. (2018) HCV-specific T cell responses during and after chronic HCV infection. Viruses. 17;10(11):645. doi: 10.3390/v10110645. 10. Schuch A, Salimi Alizei E, Heim K, Wieland D, Kiraithe MM, Kemming J, Llewellyn-Lacey S, Sogukpinar Ö, Ni Y, Urban S, Zimmermann P, Nassal M, Emmerich F, Price DA, Bengsch B, Luxenburger H, Neumann-Haefelin C, Hofmann M, Thimme R. (2019) Phenotypic and functional differences of HBV core-specific versus HBV polymerase-specific CD8+ T cells in chronically HBV-infected patients with low viral load. Gut. 68(5):905-915. doi: 10.1136/gutjnl-2018-316641.
- Address
- Department of Medicine II
University Hospital Freiburg
Hugstetter Str. 55
79106 Freiburg, Germany