Scientific Vita
Publi­cations
Con­tact

Dr.

Maike Hofmann

Academic Education and University Degrees

2007 - 2012
Ph.D. thesis, Molecular Medicine / Immunology, Institute of Immunology, Medical Center – University of Freiburg, Germany supervised by Prof. Dr. Hanspeter Pircher
2007
Diploma thesis, Molecular Medicine, Institute of Immunology, Medical Center- University of Freiburg, Germany supervised by Prof. Dr.Hanspeter Pircher
2002 - 2007
Studies in Molecular Medicine, University of Freiburg, Germany

Employment

Since 2014
Scientist, Department of Medicine II - Gastroenterology, Hepatology, Endocinology and Infectious Diseases, Medical Center - University of Freiburg, Germany
2014 - 2014
Postdoc, University spin-off cytena / Department for Microsystems Engineering, University of Freiburg, Germany
2012 - 2014
Postdoc, Institute of Immunology, Medical Center - University of Freiburg, Germany
Hoh A, Heeg M, Ni Y, Schuch A, Binder B, Hennecke N, Blum HE, Nassal M, Protzer U, Hofmann M, Urban S, Thimme R. 2015. HBV-infected HepG2hNTCPcells serve as a novel immunological tool to analyze the antiviral efficacy of CD8+ T cells in vitro. J Virol 89:7433-8
Schweier O, Hofmann M, Pircher H. 2014. KLRG1 activity is regulated by association with the transferring receptor. Eur J Immunol 44:1851-6
Hofmann M, Oschowitzer A, Kurzhals SR, Krüger CC, Pircher H. 2013. Thymus-resident+memory CD8 T cells mediate local immunity. Eur J Immunol 43:2295-304
Hechinger AK, Maas K, Dürr C, Leonhardt F, Prinz G, Marks R, Gerlach U, Hofmann M, Fisch P, Finke J, Pircher H, Zeiser R. 2013. Inhibition of protein geranylgeranylation and farnesylation protects against graft-versus-host disease via effects on CD4 effector T cells. Haematologica 98:31-40
Hofmann M, Schweier O, Pircher H. 2012. Different inhibitory capacities of human and mouse KLRG1 are linked to distinct disulfide-mediated oligomerizations. Eur J Immunol 42:2484-90
Hofmann M, Pircher H. 2011. E-cadherin promotes accumulation of a unique memory CD8 T- cell population in murine salivary glands. Proc Natl Acad Sci USA. 108:16741-6
Li Y, Hofmann M, Wang Q, Teng L, Chlewicki LK, Pircher H, Mariuzza RA. 2009. Structure of natural killer cell receptor KLRG1 bound to E-cadherin reveals basis for MHC-independent missing self recognition. Immunity 31:35-46
Rosshart S, Hofmann M, Schweier O, Pfaff AK, Yoshimoto K,Takeuchi T, Molnar E, Schamel WW, Pircher H. 2008. Interaction of KLRG1 with E-cadherin: new functional and structural insights. Eur J Immunol 38:3354-64
Address
Department of Medicine II,
University Hospital Freiburg
Hugstetterstr.55
79106 Freiburg
eMail
maike.hofmann@uniklinik-freiburg.de