Scientific Vita
Publi­cations
Con­tact

PD. Dr.

Volker Lohmann

Academic Education and University Degrees

2012
Habilitation in Experimental Virology, Heidelberg University, Germany, mentor: Prof. Dr. Ralf Bartenschlager
1993 - 1998
Ph.D. thesis, Molecular Biology, Center for Molecular Biology, Heidelberg, Germany (Grade: summa cum laude) supervised by Prof. Dr. Ralf Bartenschlager
1992 - 1993
Diploma work, Biology, University Hospital Mainz, Germany, Experimental Virology, supervised by Prof. Dr. Dietrich Falke
1987 - 1993
Study of Biology at University of Mainz, Germany

Employment

Since 02/2002
Group leader at the Department Infectious Diseases, Molecular Virology, Heidelberg University, Germany
1998 - 2002
Postdoc at the Institute for Virology, University of Mainz, Germany
Esser-Nobis K, Harak C, Schult P, Kusov Y, Lohmann V. 2015. Novel perspectives for hepatitis A virus therapy revealed by comparative analysis of hepatitis C virus and hepatitis A virus RNA replication. Hepatology 62:397-408.
Esser-Nobis K, Romero-Brey I, Ganten TM, Gouttenoire J, Harak C, Klein R, Schemmer P, Binder M, Schnitzler P, Moradpour D, Bartenschlager R, Polyak SJ, Stremmel W, Penin F, Eisenbach C, Lohmann V. 2013. Analysis of hepatitis C virus resistance to silibinin in vitro and in vivo points to a novel mechanism involving nonstructural protein 4B. Hepatology 57:953-963.
Reiss S, Harak C, Romero-Brey I, Radujkovic D, Klein R, Ruggieri A, Rebhan I, Bartenschlager R, Lohmann V. 2013. The lipid kinase phosphatidylinositol-4 kinase III alpha regulates the phosphorylation status of hepatitis C virus NS5A. PLoS Pathog 9:e1003359.
Reiss S#, Rebhan I#, Backes P, Romero-Brey I, Erfle H, Matula P, Kaderali L, Poenisch M, Blankenburg H, Hiet MS, Longerich T, Diehl S, Ramirez F, Balla T, Rohr K, Kaul A, Buhler S, Pepperkok R, Lengauer T, Albrecht M, Eils R, Schirmacher P, Lohmann V*, Bartenschlager R*. 2011. Recruitment and activation of a lipid kinase by hepatitis C virus NS5A is essential for integrity of the membranous replication compartment. Cell Host Microbe 9: 32-45. #equal contribution, *co-corresponding author
Backes P, Quinkert D, Reiss S, Binder M, Zayas M, Rescher U, Gerke V, Bartenschlager R, Lohmann V. 2010. Role of annexin A2 in the production of infectious hepatitis C virus particles. J Virol 84: 5775-5789.
Simister P, Schmitt M, Geitmann M, Wicht O, Danielson UH, Klein R, Bressanelli S, Lohmann V. 2009. Structural and functional analysis of hepatitis C virus strain JFH1 polymerase. J Virol 83:11926-11939.
Jo J, Aichele U, Kersting N, Klein R, Aichele P, Bisse E, Sewell AK, Blum HE, Bartenschlager R, Lohmann V*, Thimme R. 2009. Analysis of CD8+ T-cell-mediated inhibition of hepatitis C virus replication using a novel immunological model. Gastroenterology 136:1391-1401. *Co- corresponding author
Binder M, Kochs G, Bartenschlager R, Lohmann V. 2007. Hepatitis C virus escape from the interferon regulatory factor 3 pathway by a passive and active evasion strategy. Hepatology 46:1365-1374.
Quinkert D, Bartenschlager R, Lohmann V. 2005. Quantitative analysis of the hepatitis C virus replication complex. J Virol 79: 13594-13605.
Lohmann V, Körner F, Koch JO, Herian U, Theilmann L, Bartenschlager R. 1999. Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line. Science 285: 110-113.
Address
Department of Infectious Diseases,
Molecular Virology Medical Faculty,
Heidelberg University
Im Neuenheimer Feld 345
69120 Heidelberg
eMail
volker.lohmannn@med.uni-heidelberg.de