Scientific Vita

Dr. Dr.

Andreas Pichlmair

Academic Education and University Degrees

2004 - 2008
PhD thesis in the Immunobiology Laboratory, Cancer Research UK, London Research Institute, London, United Kingdom. Supervisor: Dr. Caetano Reis e Sousa, Doctor of Philosophy (Dr. Phil.), University College London, UK
2002 - 2003
Doctor theses (DVM) at the Department of Virology, Institute for Medical Microbiology and Hygiene, University Freiburg, Germany. Supervisor: Prof. Friedemann Weber, Doctor of Veterinary Medicine (DVM), University of Veterinary Medicine, Vienna, Austria
Diploma in Veterinary Medicine (Dipl. Vet. Med.), University of Veterinary Medicine, Vienna, Austria,
1996 - 2002
Student of Veterinary Medicine at the University of Veterinary Medicine, Vienna, Austria. Principal subject: Biotechnology


Since 07/2017
Associate Professor, Technical University Munich, Institute of Virology, Immunopathology of Viruses, Munich, Germany
Since 09/2011
Principal Investigator of the Innate Immunity Laboratory, Max-Planck Institute of biochemistry, Martinsried, Germany
2008 - 2011
Post Doc at the Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria. Supervisor: Prof. Giulio Superti Furga.
Gebhardt A, Habjan M, Benda C, Meiler A, Haas DA, Hein MY, Mann A, Mann M, Habermann B, Pichlmair A. 2015. .mRNA export through an additional cap-binding complex consisting of NCBP1 and NCBP3. Nat Commun. 2015 Sep 18;6:8192. doi: 10.1038/ncomms9192.
Habjan M, Hubel P, Lacerda L, Benda C, Holze C, Eberl CH, Mann A, Kindler E, Gil-Cruz C, Ziebuhr J, Thiel V, Pichlmair A. 2013. Sequestration by IFIT1 impairs translation of 2'O- unmethylated capped RNA. PLoS Pathog 9:e1003663.
Abbas YM, Pichlmair A, Górna MW, Superti-Furga G, Nagar B. 2013. Structural basis for viral 5′- PPP-RNA recognition by human IFIT proteins. Nature 494: 60-4.
Pichlmair A, Kandasamy K, Alvisi G, Mulhern O, Sacco R, Habjan M, Binder M, Stefanovic A, Eberle CA, Goncalves A, Bürckstümmer T, Müller A, Fauster A, Holze A, Lindsten K, Goodbourn S, Kochs G, Weber F, Bartenschlager R, Bowie AG, Bennett KL, Colinge J, Superti-Furga. G. 2012. Viral immune modulators perturb the human molecular network by common and unique strategies. Nature 487:486-90.
Pichlmair A, Lassnig C, Eberle CA, Górna MW, Baumann CL, Burkard TR, Bürckstümmer T, Stefanovic A, Krieger S, Bennett KL, Rülicke T, Weber F, Colinge J, Müller M, Superti-Furga G. 2011. IFIT1 is an antiviral protein that recognizes 5’-triphosphate RNA. Nat Immunol 12:624-30.
Schulz O, Pichlmair A, Rehwinkel J, Rogers NC, Scheuner D, Kato H, Takeuchi O, Akira S, Kaufman RJ, Reis e Sousa C. 2010. Protein kinase R contributes to immunity against specific viruses by regulating interferon mRNA integrity. Cell Host Microbe 7:354-61
Pichlmair A, Schulz O, Tan CP, Rehwinkel J, Kato H, Takeuchi O, Akira S, Way M, Schiavo G, Reis e Sousa C. 2009. Activation of MDA5 requires higher-order RNA structures generated during virus infection. J Virol 83:10761-9.
Pichlmair A, Reis e Sousa C. 2007. Innate recognition of viruses. Immunity 27:370-83. Review.
Pichlmair A, Diebold SS, Gschmeissner S, Takeuchi Y, Ikeda Y, Collins MK, Reis e Sousa C. 2007. Tubulovesicular structures within vesicular stomatitis virus G protein-pseudotyped lentiviral vector preparations carry DNA and stimulate antiviral responses via Toll-like receptor 9. J Virol 81:539-47
Pichlmair A, Schulz O, Tan CP, Näslund TI, Liljeström P, Weber F, Reis e Sousa C. 2006. RIG-I- mediated antiviral responses to single stranded RNA bearing 5’ phosphates. Science 314: 997- 1001
Immunopathology of Virus Infections
Institute of Virology
Technical University of Munich
Schneckenburger Str. 8
81675 Munich