Scientific Vita
Publi­cations
Con­tact

Prof. Dr. Dr.

Andreas Pichlmair

Academic Education and University Degrees

2004 - 2008
PhD thesis in the Immunobiology Laboratory, Cancer Research UK, London Research Institute, London, United Kingdom. Supervisor: Dr. Caetano Reis e Sousa, Doctor of Philosophy (Dr. Phil.), University College London, UK
2002 - 2003
Doctor theses (DVM) at the Department of Virology, Institute for Medical Microbiology and Hygiene, University Freiburg, Germany. Supervisor: Prof. Friedemann Weber, Doctor of Veterinary Medicine (DVM), University of Veterinary Medicine, Vienna, Austria
2002
Diploma in Veterinary Medicine (Dipl. Vet. Med.), University of Veterinary Medicine, Vienna, Austria,
1996 - 2002
Student of Veterinary Medicine at the University of Veterinary Medicine, Vienna, Austria. Principal subject: Biotechnology

Employment

Since 07/2017
Associate Professor, Technical University Munich, Institute of Virology, Immunopathology of Viruses, Munich, Germany
Since 09/2011
Principal Investigator of the Innate Immunity Laboratory, Max-Planck Institute of biochemistry, Martinsried, Germany
2008 - 2011
Post Doc at the Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria. Supervisor: Prof. Giulio Superti Furga.
1. Bergant V, Yamada S, Grass V, Tsukamoto Y, Lavacca T, Krey K, Muhlhofer MT, Wittmann S, Ensser A, Herrmann A, Vom Hemdt A, Tomita Y, Matsuyama S, Hirokawa T, Huang Y, Piras A, Jakwerth CA, Oelsner M, Thieme S, Graf A, Krebs S, Blum H, Kummerer BM, Stukalov A, Schmidt-Weber CB, Igarashi M, Gramberg T, Pichlmair A*, Kato H* (2022) Attenuation of SARS-CoV-2 replication and associated inflammation by concomitant targeting of viral and host cap 2'-O-ribose methyltransferases. EMBO J. 41(17):e111608. doi: 10.15252/embj.2022111608. *equal contribution.
2. Laudenbach BT, Krey K, Emslander Q, Andersen LL, Reim A, Scaturro P, Mundigl S, Dachert C, Manske K, Moser M, Ludwig J, Wohlleber D, Kroger A, Binder M, Pichlmair A. (2021) NUDT2 initiates viral RNA degradation by removal of 5'-phosphates. Nat Commun. 12(1):6918. doi: 10.1038/s41467-021-27239-y.
3. Stukalov A, Girault V, Grass V, Karayel O, Bergant V, Urban C, Haas DA, Huang Y, Oubraham L, Wang A, Hamad MS, Piras A, Hansen FM, Tanzer MC, Paron I, Zinzula L, Engleitner T, Reinecke M, Lavacca TM, Ehmann R, Wolfel R, Jores J, Kuster B, Protzer U, Rad R, Ziebuhr J, Thiel V, Scaturro P, Mann M, Pichlmair A. (2021) Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV. Nature. 594(7862):246-252. doi: 10.1038/s41586-021-03493-4.
4. Neufeldt CJ, Cortese M, Scaturro P, Cerikan B, Wideman JG, Tabata K, Moraes T, Oleksiuk O, Pichlmair A, Bartenschlager R. (2019) ER-shaping atlastin proteins act as central hubs to promote flavivirus replication and virion assembly. Nat Microbiol. 4(12):2416-2429. doi: 10.1038/s41564-019-0586-3.
5. Hubel P, Urban C, Bergant V, Schneider WM, Knauer B, Stukalov A, Scaturro P, Mann A, Brunotte L, Hoffmann HH, Schoggins JW, Schwemmle M, Mann M, Rice CM, Pichlmair A. (2019) A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape. Nat Immunol. 20(4):493-502. doi: 10.1038/s41590-019-0323-3.
6. Scaturro P, Stukalov A, Haas DA, Cortese M, Draganova K, Plaszczyca A, Bartenschlager R, Gotz M, Pichlmair A. (2018) An orthogonal proteomic survey uncovers novel Zika virus host factors. Nature. 561(7722):253-257. doi: 10.1038/s41586-018-0484-5.
7. Holze C, Michaudel C, Mackowiak C, Haas DA, Benda C, Hubel P, Pennemann FL, Schnepf D, Wettmarshausen J, Braun M, Leung DW, Amarasinghe GK, Perocchi F, Staeheli P, Ryffel B, Pichlmair A. (2018) Oxeiptosis, a ROS-induced caspase-independent apoptosis-like cell-death pathway. Nat Immunol. 19(2):130-140. doi: 10.1038/s41590-017-0013-y.
8. Pichlmair A, Kandasamy K, Alvisi G, Mulhern O, Sacco R, Habjan M, Binder M, Stefanovic A, Eberle CA, Goncalves A, Burckstummer T, Muller AC, Fauster A, Holze C, Lindsten K, Goodbourn S, Kochs G, Weber F, Bartenschlager R, Bowie AG, Bennett KL, Colinge J, Superti-Furga G. (2012) Viral immune modulators perturb the human molecular network by common and unique strategies. Nature. 26;487(7408):486-90. doi: 10.1038/nature11289.
9. Pichlmair A, Lassnig C, Eberle CA, Gorna MW, Baumann CL, Burkard TR, Burckstummer T, Stefanovic A, Krieger S, Bennett KL, Rulicke T, Weber F, Colinge J, Muller M, Superti-Furga, G. (2011) IFIT1 is an antiviral protein that recognizes 5'-triphosphate. RNA Nat Immunol. 12(7):624-30. doi: 10.1038/ni.2048.
10. Pichlmair A, Schulz O, Tan CP, Naslund TI, Liljestrom P, Weber F, Reis e Sousa C. (2006) RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates. Science. 314(5801):997-1001. doi: 10.1126/science.1132998.
Address
Immunopathology of Virus Infections
Institute of Virology
Technical University of Munich
Schneckenburger Str. 8
81675 Munich
eMail
andreas.pichlmair@tum.de