Scientific Vita
Publi­cations
Con­tact

Dr.

Dirk Wohlleber

Academic Education and University Degrees

2003 - 2006
Ph.D. work, Biochemistry, Interfakultäres Institut für Biochemie, Tübingen, Germany supervised by Prof. Probst
2003 - 2003
Diploma work, Biochemistry, Interfakultäres Institut für Biochemie, Tübingen, Germany supervised by Prof. Probst
1998 - 2003
Study of Biochemistry at the University of Tübingen, Germany

Employment

Since 04/2014
Research group leader at the Institute of Molecular Immunology, Technische Universität München, Germany
2006 – 2014
Postdoc at the Institutes of Molecular Medicine and Experimental Immunology, University of Bonn, Germany
Schölzel K, Schildberg FA, Börner C, Geiger S, Kurts C, Heikenwälder M, Knolle PA, Wohlleber D. 2014. Cross-allocation of MHC-class-I molecules among liver sinusoidal cells facilitates hepatic immune surveillance. J Hepatol.61:600-8
Huang LR, Wohlleber D, Reisinger F, Jenne CN, Cheng RL, Abdullah Z, Schildberg FA, Odenthal M, Dienes HP, van Rooijen N, Schmitt E, Garbi N, Croft M, Kurts C, Kubes P, Protzer U, Heikenwalder M, Knolle PA. 2013. Intrahepatic myeloid-cell aggregates enable local proliferation of CD8+ T cells and successful immunotherapy against chronic viral liver infection. Nat Immunol 14:574-83
Böttcher JP, Schanz O, Wohlleber D, Abdullah Z, Debey-Pascher S, Staratschek-Jox A, Höchst B, Hegenbarth S, Grell J, Limmer A, Atreya I, Neurath MF, Busch DH, Schmitt E, van Endert P, Kolanus W, Kurts C, Schultze JL, Diehl L, Knolle PA. 2013. Liver-Primed Memory T Cells Generated under Noninflammatory Conditions Provide Anti-infectious Immunity. Cell Rep 3:779-95
Wohlleber D, Kashkar H, Gärtner K, Frings MK, Odenthal M, Hegenbarth S, Börner C, Arnold B, Hämmerling G, Nieswandt B, van Rooijen N, Limmer A, Cederbrant K, Heikenwalder M, Pasparakis M, Protzer U, Dienes HP, Kurts C, Krönke M, Knolle PA. 2012. TNF-induced target cell killing by CTL activated through cross-presentation. Cell Rep 2:478-87
Hösel M, Broxtermann M, Janicki H, Esser K, Arzberger S, Hartmann P, Gillen S, Kleef J, Stabenow D, Odenthal M, Knolle P, Hallek M, Protzer U, Büning H. 2012. Toll-like receptor 2-mediated innate immune response in human nonparenchymal liver cells toward adeno-associated viral vectors. Hepatology 55:287-97.
Böttcher JP, Knolle PA, Stabenow D. 2011. Mechanisms balancing tolerance and immunity in the liver. Dig Dis 29:384-90.
Stabenow D, Frings M, Trück C, Gärtner K, Föerster I, Kurts C, Tüting T, Odenthal M, Dienes HP, Cederbrant K, Protzer U, Knolle PA. 2010. Bioluminescence imaging allows measuring CD8 T cell function in the liver. Hepatology 51:1430-7
Schurich A, Böttcher JP, Burgdorf S, Penzler P, Hegenbarth S, Kern M, Dolf A, Endl E, Schultze J, Wiertz E, Stabenow D, Kurts C, Knolle P. 2009. Distinct kinetics and dynamics of cross- presentation in liver sinusoidal endothelial cells compared to dendritic cells. Hepatology 50:909- 919.
Schurich A, Berg M, Stabenow D, Böttcher J, Kern M, Schild HJ, Kurts C, Schuette V, Burgdorf S, Diehl L, Limmer A, Knolle PA. 2010. Dynamic regulation of CD8 T cell tolerance induction by liver sinusoidal endothelial cells. J Immunol 184:4107-14.
Stabenow D, Probst H, van Betteraey-Nikoleit M. 2005. Cdk2 activity is dispensable for triggering replicon initiation after transient hypoxia in T24 cells. FEBS J 272:5623-34.
Address
Institute of Molecular Immunology and Experimental Oncology
Klinikum rechts der Isar
Technische Universität München
Trogerstr. 9
81675 München
eMail
dirk.wohlleber@tum.de