Scientific Vita
Publi­cations
Con­tact

Prof. Dr.

Adelheid Cerwenka

Academic Education and University Degrees
2007
Venia Legendi for Immunology, University of Heidelberg, Faculty of Medicine, Heidelberg, Germany, mentor Prof. Stefan Meuer, Heidelberg, Germany
1991 - 1995
PhD, Institute of Immunology, University of Vienna, Austria, supervised by Prof. Walter Knapp
1986 - 1991
Diploma in Pharmacy, Institute of Immunology, University of Vienna, Austria

Employment
2017 - today
Full Professor of Immunbiochemistry, Heidelberg University, Medical Faculty Mannheim, Germany
2003 - 2017
Head of Boveri Junior Group “Innate Immunity” at the German Cancer Research Center, Heidelberg, Germany
2001 - 2003
Head of Laboratory, Division of Autoimmune Diseases, Novartis Research Institute, Vienna, Austria
1998 - 2001
Post-doc, DNAX Research Institute and University of California, San Francisco, USA, with Prof. Lewis L. Lanier
1996 -1998
Post-doc, University of California, San Diego, CA, USA and at the Trudeau Institute, NY, USA, with Prof. Richard W. Dutton
1. Siegler JJ, Correia MP, Hofman T, Prager I, Birgin E, Rahbari NN, Watzl C, Stojanovic A, Cerwenka A. (2022) Human ILC3 exert TRAIL-mediated cytotoxicity towards cancer cells. Front Immunol. 13:742571. doi: 10.3389/fimmu.2022.742571.
2. Ni J, Wang X, Stojanovic A, Zhang Q, Wincher M, Bühler L, Arnold A, Correia MP, Winkler M, Koch PS, Sexl V, Höfer T, Cerwenka A. (2020) Single-cell RNA sequencing of tumor-infiltrating NK cells reveals that inhibition of transcription factor HIF-1α unleashes NK cell activity. Immunity. 52,1075-1087.e8. doi: 10.1016/j.immuni.2020.05.001.
3. Schuch A, Zecher BF, Müller PA, Correia MP, Daul F, Rennert C, Tauber C, Schlitt K, Boettler T, Neumann-Haefelin C, Hengel H, Pircher H, Cerwenka A, Thimme R, Hofmann M. (2019) NK-cell responses are biased towards CD16-mediated effector functions in chronic hepatitis B virus infection. J Hepatol. 70(3):351-360. doi: 10.1016/j.jhep.2018.10.006.
4. Correia MP, Stojanovic A, Bauer K, Juraeva D, Tykocinski LO, Lorenz HM, Brors B, Cerwenka A. (2018) Distinct human circulating NKp30+FcεRIγ+CD8+ T cell population exhibiting high natural killer-like antitumor potential. PNAS. 115,E5980-E5989. doi: 10.1073/pnas.1720564115.
5. Pahl JHW, Koch J, Gotz JJ, Arnold A, Reusch U, Gantke T, Rajkovic E, Treder MS, Cerwenka A. (2018) CD16A activation of NK cells promotes NK cell proliferation and memory-like cytotoxicity against cancer cells. Cancer Immunol Res. 6,517-527. doi: 10.1158/2326-6066.
6. Pollmann J, Götz JJ, Rupp D, Strauss O, Granzin M, Grünvogel O, Mutz P, Kramer C, Lasitschka F, Lohmann V, Björkström NK, Thimme R, Bartenschlager R, Cerwenka A. (2018) Hepatitis C virus-induced natural killer cell proliferation involves monocyte-derived cells and the OX40/OX40L axis. J Hepatol. 68,421-430. doi: 10.1016/j.jhep.2017.10.021.
7. Cerwenka A, Lanier LL. (2016) NK cell memory in viral infection, inflammation and cancer. Nat Rev Immunol. 16,112-23. doi:10.1038/nri.2015.9.
8. Rölle A, Pollmann J, Ewen E, Halenius A, Hengel H, Cerwenka A. (2014) IL-12 producing monocytes and HLA-E drive NKG2C+ NK cell expansion in HCMV infection. J Clin Invest. 77440. doi: 10.1172/JCI77440.
9. Ni J, Miller M, Stojanovic A, Garbi N, Cerwenka A. (2012) Sustained effector function of IL-12/15/18 preactivated NK cells against established tumors. J Exp Med. 209,2351-2365. DOI:10.1084/jem.20120944.
10. Cerwenka A, Bakker ABH, McClanahan T, Wagner J, Wu J, Phillips JH, Lanier LL. (2000) Retinoic acid early inducible genes define a ligand family for the activating NKG2D receptor in mice. Immunity. 12,721-727. doi: 10.1016/s1074-7613(00)80222-8.
Address
Office: Tridomus, Haus C, Ebene 5
Ludolf-Krehl-Strasse 13 - 17
Lab: Tridomus, Haus B, Ebene 3
Ludolf-Krehl-Strasse 7 - 11
D-68167 Mannheim
eMail
Adelheid.Cerwenka@medma.uni-heidelberg.de