Habilitation in Experimental Virology, Heidelberg University, Germany, mentor: Prof. Dr. Ralf Bartenschlager
Scientific Vita
Publications
Contact

APL Prof. Dr.
Volker Lohmann
Academic Education and University Degrees
2012
1993 - 1998
Ph.D. thesis, Molecular Biology, Center for Molecular Biology, Heidelberg, Germany (Grade: summa cum laude) supervised by Prof. Dr. Ralf Bartenschlager
1992 - 1993
Diploma work, Biology, University Hospital Mainz, Germany, Experimental Virology, supervised by Prof. Dr. Dietrich Falke
1987 - 1993
Study of Biology at University of Mainz, Germany
Employment
Since 2020
Head of section "Virus-Host-Interactions"
Since 2019
Apl. Prof. at Heidelberg University
Since 2018
Deputy head of Department of Infectious Diseases, Molecular Virology
Since 02/2002
Group leader at the Department Infectious Diseases, Molecular Virology, Heidelberg University, Germany
1998 - 2002
Postdoc at the Institute for Virology, University of Mainz, Germany
Schult P, Roth H, Adams RL, Mas C, Imbert L, Orlik C, Ruggieri A, Pyle AM, Lohmann V. 2018. microRNA-122 amplifies hepatitis C virus translation by shaping the structure of the internal ribosomal entry site. Nat Commun. 9(1):2613.Grünvogel O, Colasanti O, Lee JY, Klöss V, Belouzard S, Reustle A, Esser-Nobis K, Hesebeck-Brinckmann J, Mutz P, Hoffmann K, Mehrabi A, Koschny R, Vondran FWR, Gotthardt D, Schnitzler P, Neumann-Haefelin C, Thimme R, Binder M, Bartenschlager R, Dubuisson J, Dalpke AH, Lohmann V. 2018. Secretion of Hepatitis C Virus Replication Intermediates Reduces Activation of Toll-Like Receptor 3 in Hepatocytes. Gastroenterology. 154(8):2237-2251.Doerflinger SY, Cortese M, Romero-Brey I, Menne Z, Tubiana T, Schenk C, White PA, Bartenschlager R, Bressanelli S, Hansman GS, Lohmann V. 2017. Membrane alterations induced by nonstructural proteins of human norovirus. PLoS Pathog. 13(10):e1006705. Harak C, Meyrath M, Romero-Brey I, Schenk C, Gondeau C, Schult P, Esser-Nobis K, Saeed M, Neddermann P, Schnitzler P, Gotthardt D, Perez-Del-Pulgar S, Neumann-Haefelin C, Thimme R, Meuleman P, Vondran FW, Francesco R, Rice CM, Bartenschlager R, Lohmann V. 2016. Tuning a cellular lipid kinase activity adapts hepatitis C virus to replication in cell culture. Nat Microbiol. 2:16247.Esser-Nobis K, Schmidt J, Nitschke K, Neumann-Haefelin C, Thimme R, Lohmann V. 2016. The cyclophilin-inhibitor alisporivir stimulates antigen presentation thereby promoting antigen-specific CD8(+) T cell activation. J Hepatol. 64(6):1305-14. Esser-Nobis K, Harak C, Schult P, Kusov Y, Lohmann V. 2015. Novel perspectives for hepatitis A virus therapy revealed by comparative analysis of hepatitis C virus and hepatitis A virus RNA replication. Hepatology. 62(2):397-408.Esser-Nobis K, Romero-Brey I, Ganten TM, Gouttenoire J, Harak C, Klein R, Schemmer P, Binder M, Schnitzler P, Moradpour D, Bartenschlager R, Polyak SJ, Stremmel W, Penin F, Eisenbach C, Lohmann V. 2013. Analysis of hepatitis C virus resistance to silibinin in vitro and in vivo points to a novel mechanism involving nonstructural protein 4B. Hepatology. 57(3):953-963. Reiss S°, Rebhan I°, Backes P, Romero-Brey I, Erfle H, Matula P, Kaderali L, Poenisch M, Blankenburg H, Hiet MS, Longerich T, Diehl S, Ramirez F, Balla T, Rohr K, Kaul A, Buhler S, Pepperkok R, Lengauer T, Albrecht M, Eils R, Schirmacher P, Lohmann V*, Bartenschlager R*. 2011. Recruitment and activation of a lipid kinase by hepatitis C virus NS5A is essential for integrity of the membranous replication compartment. Cell Host Microbe. 9(1): 32-45. (°equal contribution) (*co-corresponding author)Jo J, Aichele U, Kersting N, Klein R, Aichele P, Bisse E, Sewell AK, Blum HE, Bartenschlager R, Lohmann V*, R. Thimme*. 2009. Analysis of CD8+ T-cell-mediated inhibition of hepatitis C virus replication using a novel immunological model. Gastroenterology. 136(4):1391-1401. (*co-corresponding author)Lohmann V, Körner F, Koch JO, Herian U, Theilmann L, Bartenschlager R. 1999. Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line. Science. 285 (5424): 110-113.
- Address
- Department of Infectious Diseases,
Molecular Virology Medical Faculty,
Heidelberg University
Im Neuenheimer Feld 344
69120 Heidelberg - volker.lohmannn@med.uni-heidelberg.de