Scientific Vita


Claudia Beisel

2003 – 2010
Study of Medicine, University Cologne, Germany
2010 – 2011
Prof. Dr. Oliver Cornely, Infectious Disease Department, University-Hospital Cologne, “Fungiscope – Global Rare Fungal Infection Registry”
Since 09/2022
Medical specialist/ Physician Scientist, Department for Internal Medicine IV, University Hospital Heidelberg, Germany
Specialist in Infectious Diseases (German Society of Infectious Diseases and Medical Council, Hamburg)
Specialist in Immunology (German Society of Immunology)
Specialist for Internal Medicine (Medical Council, Hamburg)
Diploma in Tropical Medicine (Bernhard Nocht Institute Hamburg)
2014 – 2021
PostDoc “Sex-related differences in innate immunity to viral infections.“ Leibniz Institute for experimental Virology, Virus Immunology, Hamburg, Germany Prof. Dr. M. Altfeld
2010 – 08/2022
Residency and Research Associate I. Medical Department for Internal Medicine University Hospital Hamburg-Eppendorf Prof. Dr. A.W. Lohse, Prof. Dr. S. Huber
Beisel C, Jordan-Paiz A, Köllmann S, Ahrenstorf AE, Padoan B, Barkhausen T, Altfeld M. Sex differences in human B cell expression of IRF5 are associated with higher production of TNF-α in females in response to TLR9.” (Biol Sex Differ. 2023). doi: 10.1186/s13293-023-00495-x

Cords L, Woost R, Kummer S, Brehm TT, Kluge S, Schmiedel S, Jordan S, Lohse AW, Altfeld M, Addo MM, Schulze zur Wiesch J, Beisel C. Downregulation of IRF5 in dendritic cells of SARS-CoV-2 infected patients is associated with an impaired TLR7-induced inflammatory cytokine response. Cytokine 2023. doi: 10.1016/j.cyto.2022.156109

de Leuw P, Beisel C, Schulze zur Wiesch J. Virushepatitis. Brodt/ Stille, Antibiotika-Therapie: Klinik und Praxis der antiinfektiösen Behandlung, Thieme Verlag, Auflage 2023 (Book Chapter).

Wildner HN, Walker A, Brauneck F, Kessler M, Peine S, Huber S, Haag F, Beisel C, Timm J, Schulze zur Wiesch J. Transcriptional pattern analysis of virus-specific CD8+ T cells in hepatitis C infection: increased expression of TOX and Eomesodermin during and after persistent antigen recognition. Front. Immunology 2022. doi: 10.3389/fimmu.2022.886646

Plochg B, Englert H, Rangaswamy C, Konrath S, Malle M, Lampalzer S, Beisel C, Wollin S, Frye M, Aberle J, Kluwe J, Renné T, Mailer M. Liver damage promotes atherogenic T-cell responses against apolipoprotein B-100. J Intern Med. 2021. doi: 10.1111/joim.13434

Graf LM, Rosenkranz SM, Hoelzemer A, Hagel C, Goebell E, Friese M, Addo MM, Schulze zur Wiesch J, Beisel C. 37 consecutive cases of progressive multifocal leukencephalopthy (PML) at a German tertiary-care hospital: a retrospective observational study. Front Neurol. 2021. doi: 10.3389/fneur.2021.632535

Beisel C, Herrmann M, Piecha F, Buescher G, Lampalzer S, Schulze zur Wiesch J. Real-world effectiveness of glecaprevir/pibrentasvir (GLE/PIB) for chronic hepatitis C infection: Results from a German single-center cohort study. Hep. Monthly 2021.

Beisel C, Ziegler S, Griesbeck M, Hildebrandt H, Lohse AW, Altfeld M. TLR7-mediated activation of XBP1 correlates with the IFNα production in humans. Cytokine 2017. doi: 10.1016/j.cyto.2017.04.006

Ziegler S, Beisel C, Sutter K, Griesbeck M, Hildebrandt H, H Hagen S, Dittmer U, Altfeld M. Human pDCs display sex-specific differences in type I interferon subtypes and interferon α/β receptor expression. Eur J Immunol. 2016. doi: 10.1002/eji.201646725

Griesbeck M, Ziegler S, Laffont S, Tomezsko P, Sharei A, Chauveau L, Smith N, Kourjian G, Porichis F, Meghan H, Palmer CD, Sirignano M, Beisel C, Hildebrandt H, Cénac C, Villani AC, Diefenbach T, LeGall S, Schwartz O, Herbeuval JP, Autran B, Guéry JC, Chang JJ & Altfeld M. Sex differences in plasmacytoid dendritic cell levels of IRF5 drive higher IFNα production in women. J Immunol. 2015. doi: 10.4049/jimmunol.1501684
Department for Internal Medicine IV
Im Neuenheimer Feld
University Hospital Heidelberg, Germany