Scientific Vita


Viet Loan Dao Thi

Academic Education and University Degree
from 04/2018
Chica and Heinz Schaller research group leader at Heidelberg University
2015 - 2018
Postdoc, Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, USA
2012 - 2014
Postdoc, Institute of Microbiology of the University Hospital Centre Vaudois and of the University of Lausanne, Lausanne, Switzerland
2005 - 2006
Diploma work, Robert Koch Institute, Berlin
2003 - 2004
MSc, Dongseo University in Pusan, South Korea
2000 - 2006
Dipl.-Ing., Berlin Institute of Technology, Germany
2007 - 2011
Ph.D., Ecole Normale Superieur de Lyon, France
1. Maurer L, El Andari J, Rapti K, Spreyer L, Steinmann E, Grimm D*, Dao Thi VL*. (2022) Induction of Hepatitis E virus anti-ORF3 antibodies from systemic administration of a muscle-specific adeno-associated virus (AAV) vector. Viruses. 14(2),266. doi: 10.3390/v14020266. *equal contribution.
2. Zhang C, Freistaedter A, Schmelas C, Gunkel M, Dao Thi VL*, Grimm D*. (2021) A RNA interference/adeno-associated virus vector-based combinatorial gene therapy approach against hepatitis E virus. Hepatol Commun. 6(4):878-888. doi: 10.1002/hep4.1842. *equal contribution.
3. Dao Thi VL†, Herbst K, Boerner K, Meurer M, Kremer PML, Kirrmaier D, Freistaedter A, Papagiannidis D, Galmozzi C, Stanifer ML, Boulant S, Klein S, Chlanda P, Khalid D, Barreto Mirranda I, Schnitzler P, Kräusslich HG, Knop M, Anders S. (2020) A colorimetric RT-LAMP assay and LAMP-sequencing for detecting SARS-CoV-2 RNA in clinical samples. Sci Transl Med. 12(556):eabc7075. doi: 10.1126/scitranslmed.abc7075. †corresponding author.
4. Dao Thi VL†, Wu X, Belote RL, Andreo U, Takacs CN, Fernandez JP, Vale-Silva LA, Decker CC, Fu RM, Qu B, Uryu K, Molina H, Saeed M, Steinmann E, Urban S, Singarja RR, Schneider WM, Simon SM, Rice CM. (2020) Stemm cell-derived polarized hepatocytes. Nat Commun. 11(1):1677. doi: 10.1038/s41467-020-15337-2. †corresponding author.
5. Chung H, Calis JJA, Wu X, Sun T, Yu Y, Sarbanes SL, Dao Thi VL, Shilvock AR, Hoffmann HH, Rosenberg BR, Rice CM. (2018) Human ADAR1 prevents endogenous RNA from triggering translational shutdown. Cell. 172(4):811-824. doi: 10.1016/j.cell.2017.12.038.
6. Wu X*, Dao Thi VL*, Liu P, Takacs CN, Xiang K, Andrus L, Gouttenoire J, Moradpour D, Rice CM. (2018) Pan-genotype hepatitis E virus replication in stem cell-derived hepatocellular systems. Gastroenterology. 154(3):663-647. doi: 10.1053/ j.gastro. 2017.10.041. *equal contribution.
7. Wu X, Dao Thi VL, Huang Y, Billerbeck E, Saha D, Hoffmann HH, Wang Y, Vale Silva LA, Sarbanes S, Sun T, Andrus L, Quirk C, MacDonald MR, Schneider WM, An X, Rosenberg BR, Rice CM. (2018) Intrinsic immunity shapes viral resistance of stem cells Cell. 172(3):423-438. doi: 10.1016/j.cell.2017.11.018
8. Takacs CN, Andreo U, Dao Thi VL, Wu X, Gleason CE, Itano MS, Spitz G, Belote RL, Flatley BR, Scull MA, Rice CM, Simon SM. (2017) Differential regulation of lipoprotein and hepatitis C virus secretion by Rab1b. Cell Rep. 21(2):431-441. doi: 10.1016/j.celrep.2017.09.053.
9. Dao Thi VL, Debing Y, Wu X, Rice CM, Neyts J, Moradpour D*, Gouttenoire J*. (2016) Sofosbuvir inhibits Hepatitis E virus replication in vitro and results in an additive effect when combined with ribavirin. Gastroenterology. 150:82-85. doi: 10.1053/j.gastro.2015.09.011. *equal contribution.
10. Dao Thi VL, Granier C, Zeisel MB, Guérin M, Mancip J, Granio O, Penin F, Lavillette D, Bartenschlager R, Baumert TF, Cosset FL, Dreux M. (2012) Characterization of hepatitis C virus particle subpopulations reveals multiple usage of the scavenger receptor BI for entry steps. J Biol Chem. 287:31242-57. doi: 10.1074/jbc.M112.365924.
Department of Infectious Deseases, Virology
Medical Faculty, Heidelberg University
Im Neuenheimer Feld 344
69120 Heidelberg