Scientific Vita

Prof. Dr.

Karsten Rippe

Academic Education and University Degrees
Since 2018
Professor (W3) at the University of Heidelberg
Since 2017
Head of the Division of Chromatin Networks at the DKFZ and the Bioquant Center, Heidelberg
2007 - 2017
Head of the Research Group Genome Organization & Function at the DKFZ and the Bioquant, Heidelberg
2001 - 2007
Group leader of the Molecular Biophysics Group at the Kirchhoff-Institut für Physik, University of Heidelberg
1994 - 2001
Scientist at the German Cancer Research Center (DKFZ) in the Divisions Biophysics of Macromolecules (head: Jörg Langowski) and Molecular Genetics (head: Peter Lichter)
1992- 1994
Postdoctoral fellow, Dept. of Chemistry and Biochemistry (head: Peter von Hippel), Institute for Molecular Biology, University of Oregon, Eugene, USA
Mallm JP, Iskar M, Ishaque N, Klett LC, Kugler SJ, Muino JM, Teif VB, Poos AM, Großmann S, Erdel F, Tavernari D, Koser SD, Schumacher S, Brors B, König R, Remondini D, Vingron M, Stilgenbauer S, Lichter P, Zapatka M, Mertens D, Rippe K. 2019. Linking aberrant chromatin features in chronic lymphocytic leukemia to deregulated transcription factor networks. Mol Syst Biol. 5: e8339.
Rademacher A, Erdel F, Trojanowski J, Schumacher S, Rippe K. 2017. Real-time observation of light-controlled transcription in living cells. J Cell Sci. 130: 4213-4224.
Caudron-Herger M, Pankert T, Seiler J, Nemeth A, Voit R, Grummt I, Rippe K. 2015. Alu element-containing RNAs maintain nucleolar structure and function. EMBO J. 34: 2758-2771.
Osterwald S, Deeg KI, Chung I, Parisotto D, Wörz S, Rohr K, Erfle H, Rippe K. 2015. PML induces compaction, partial TRF2 depletion and DNA damage signaling at telomeres and promotes alternative lengthening of telomeres. J Cell Sci. 128: 1887-1900.
Müller-Ott K, Erdel F, Matveeva A, Hahn M, Mallm JP, Rademacher A, Marth C, Zhang Q, Kaltofen S, Schotta G, Höfer T, Rippe K. 2014. Specificity, propagation and memory of pericentric heterochromatin. Mol Syst Bio. 10: 746.
Baum M, Wachsmuth M, Erdel F, Rippe K. 2014. Retrieving the intracellular topology from multi-scale protein mobility mapping in living cells. Nat Commun. 5: 4494.
Teif VB, Vainshtein Y, Caudron-Herger M, Mallm JP, Marth C, Höfer T, Rippe K. 2012. Genome-wide nucleosome positioning during embryonic stem cell development. Nat Struct Mol Biol. 19: 1185-1191.
Erdel F, Schubert T, Marth C, Längst G, Rippe K. 2010. Human ISWI chromatin-remodeling complexes sample nucleosomes via transient binding reactions and become immobilized at active sites. Proc Natl Acad Sci USA. 107: 19873-19878.
Rippe K, Schrader A, Riede P, Strohner R, Lehmann E, Längst G. 2007. DNA sequence- and conformation-directed positioning of nucleosomes by chromatin-remodeling complexes. Proc Natl Acad Sci USA 104. 15635-15640.
Dekker J, Rippe K, Dekker M, Kleckner N. 2002. Capturing chromatin conformation. Science. 295, 1306-1311
Deutsches Krebsforschungszentrum & BioQuant
Im Neuenheimer Feld 267 - BQ 24
69120 Heidelberg