Scientific Vita

Dr. Dr.

Michael Dill

Academic Education and University Degrees
Swiss Board Certification for General Internal Medicine
Doctor of Philosophy (Cell Biology), Faculty of Science, University of Basel, Switzerland (grade: summa cum laude), supervised by Prof. Dr. Heim
Doctor of Medicine, Faculty of Medicine, University of Basel, Switzerland, supervised by Prof. Dr. Heim
2009 – 2012
MD-PhD Program funded by the Swiss National Science Foundation, Faculty of Science, University of Basel, Switzerland
Swiss Federal Diploma of Medicine
2002 – 2008
Medical School, University of Basel, Switzerland
Since 2021
Attending Physician, Internal Medicine IV, Gastroenterology, University Hospital Heidelberg, Germany
Since 2021
Max Eder Research Group Leader, German Cancer Research Center (DKFZ), Heidelberg, Germany
2019 – 2021
Physician, Internal Medicine IV, Gastroenterology, University Hospital Heidelberg, Germany
2015 – 2019
Postdoctoral Fellow, Camargo Lab, Stem Cell Program, Boston Children’s Hospital;in joint appointment at Dept. of Stem Cell and Regenerative Biology, Harvard University, and Dept. of Pediatrics, Harvard Medical School, Boston, MA, USA
Clinical fellow, Division of Gastroenterology and Hepatology, University Hospital Basel, Switzerland
2014 – 2015
Residency at Department of Internal Medicine, University Hospital Basel, Switzerland
2012 – 2014
Residency at University Clinic of Internal Medicine Liestal, Kantonsspital Baselland, Switzerland
2009 – 2012
Clinical and research fellow, Division of Gastroenterology and Hepatology, University Hospital Basel, Switzerland
Cheung P.*, Xiol J.*, Dill M.T., Yuan W.-C., Panero R., Roper J., Garcia-Osorio F., Maglic D., Li Q., Gurung B., Yilmaz Ö.H., Mao J., Camargo F.D., Regenerative reprogramming of the intestinal stem cell state via Hippo signaling suppresses metastatic colorectal cancer Cell Stem Cell. 2020 Oct 1;27(4):590-604. (* equal contribution)

Pepe-Mooney B.J.*, Dill M.T.*, Alemany A., Ordovas-Montanes J., Matsushita Y., Rao A., Sen A., Miyazaki M., Anakk S., Dawson P.A., Ono N., Shalek A.K., van Oudenaarden A., Camargo F.D. Single-cell analysis of the liver epithelium reveals dynamic heterogeneity and an essential role for YAP in homeostasis and regeneration Cell Stem Cell. 2019 Jul 3;25(1):23-38. (* equal contribution)

Planas-Paz l., Orsini V., Boulter L., Calabrese D., Pikiolek M., Nigsch F., Xie Y., Roma G., Donovan A., Marti P., Beckmann N., Dill M.T., Carbone W., Bergling S., Isken A., Mueller M., Kinzel B., Yang Y., Mao X., Nicholson T.B., Zamoni R., Capodieci P., Valdez R., Rivera D., Loew A., Ukomadu C., Terracciano L.M., Bouwmeester T., Cong F., Heim M.H., Forbes S.J., Ruffner H., Tchorz J.S., The RSPO-LGR4/5-ZNRF3/RNF43 module controls liver zonation and size Nat Cell Biol. 2016 May;18(5):467-79.

Wieland S., Makowska Z., Campana B., Calabrese D., Dill M.T., Chung J., Chisari F.V., Heim M.H., Simultaneous detection of hepatitis C virus and interferon stimulated gene expression in infected human liver Hepatology. 2014 Jun;59(6):423-33.

Dill M.T., Makowska Z., Trincucci G., Gruber A.J., Vogt J.E., Filipowicz M., Calabrese D., Krol I., Lau D.T., Terracciano L., van Nimwegen E., Roth V., Heim M.H., Pegylated IFN-α regulates hepatic gene expression through transient Jak/STAT activation J Clin Invest. 2014 Apr;124(4):1568-81.

Morikawa K., Gouttenoire J., Hernandez C., Dao Thi V.L., Tran H.T.L., Lange C.M., Dill M.T., Heim M.H., Donzé O., Penin F., Quadroni M., Moradpour D., Quantitative proteomics identifies the membrane-associated peroxidase GPx8 as cellular substrate of the hepatitis C virus NS3-4A protease Hepatology. 2014 Feb;59(2):423-33.

Dill M.T., Tornillo L., Fritzius T., Terracciano L., Semela D., Bettler B., Heim M.H., Tchorz J.S., Constitutive Notch2 signaling induces hepatic tumors in mice Hepatology. 2013 Apr;57(4):1607-19.

Dill M.T.*, Makowska Z.*, Duong F.H.T., Merkofer F., Filipowicz M., Baumert T.F., Tornillo L., Terracciano L., Heim M.H., Interferon-γ-stimulated genes, but not USP18, are expressed in livers of patients with acute hepatitis C Gastroenterology. 2012 Sep;143(3):777-786. (* equal contribution)

Dill M.T.*, Rothweiler S.*, Djonov V., Hlushchuk R., Tornillo L., Terracciano L., Radtke F., Heim M.H., Semela D., Disruption of Notch1 induces vascular remodeling, intussusceptive angiogenesis and angiosarcomas in livers of mice Gastroenterology. 2012 Apr;142(4):967-977. (* equal contribution)

Dill M.T.*, Duong F.H.T.*, Vogt J.E., Bibert S., Bochud P.Y., Terracciano L., Papassotiropoulos A., Roth V., Heim M.H., Interferon-induced gene expression is a stronger predictor of treatment response than IL28B genotype in patients with hepatitis C Gastroenterology. 2011 Mar;140(3):1021-1031. (* equal contribution)
Department of Internal Medicine IV, Gastroenterology
Heidelberg University Hospital
Im Neuenheimer Feld 410
69120 Heidelberg