Scientific Vita

Dr. rer. nat.

Immanuel Anton Andrä

10/2004 - 06/2012
Study of Biology at the Technical University of Munich
06/2012 – 04/2020
Institute for Med. Microbiology, Immunology and Hygiene, “Characterization of cell alterations caused by fluorescence activated cell sorting and development of new technical sorting approaches”. (Supervisor: Prof. Dr. med. Dirk H. Busch)
2016 – 2022
Manager Core Facility CyTUM MIH and Postdoctoral Fellow at the Institue for Medical Microbiology, Immunology and Hygiene
2022 – 2023
Leader of the Core Facility CyTUM MIH
1. Andrä I., Ulrich H., Dürr S., Soll D., Henkel L., Angerpointner C., Ritter J., Przibilla S., Stadler H., Effenberger M., Busch D.H., Schiemann M. 2020. An Evaluation of T-Cell Functionality After Flow Cytometry Sorting Revealed p38 MAPK Activation. Cytometry. Part A. 97, 171-183. doi:10.1002/cyto.a.23964
2. Florian M.C., Nattamai K.J., Dorr K., Marka G., Uberle B., Vas V., Eckl C., Andrä I., Schiemann M., Oostendorp R.A., Scharffetter-Kochanek K., Kestler H.A., Zheng Y., Geiger H. 2013. A canonical to non-canonical Wnt signalling switch in haematopoietic stem-cell ageing. Nature 503, 392-396. doi:10.1038/nature12631.
3. Grassmann S., Pachmayr L.O., Leube J., Mihatsch L., Andrae I., Flommersfeld S., Oduro J., Cicin-Sain L., Schiemann M., Flossdorf M., Buchholz V.R. 2019. Distinct Surface Expression of Activating Receptor Ly49H Drives Differential Expansion of NK Cell Clones upon Murine Cytomegalovirus Infection. Immunity 50, 1391-1400 e1394. doi:10.1016/j.immuni.2019.04.015.
4. Kälin R.E., Cai L., Li Y., Zhao D., Zhang H., Cheng J., Zhang W., Wu Y., Eisenhut K., Janssen P., Schmitt L., Enard W., Michels F., Fluh C., Hou M., Kirchleitner S.V., Siller S., Schiemann M., Andrä I., Montanez E., Giachino C., Taylor V., Synowitz M., Tonn J.C., von Baumgarten L., Schulz C., Hellmann I., Glass R. 2021. TAMEP are brain tumor parenchymal cells controlling neoplastic angiogenesis and progression. Cell Syst 12, 248-262 e247. doi:10.1016/j.cels.2021.01.002.
5. Müller T.R., Jarosch S., Hammel M., Leube J., Grassmann S., Bernard B., Effenberger M., Andrä I., Chaudhry M.Z., Kauferle T., Malo A., Cicin-Sain L., Steinberger P., Feuchtinger T., Protzer U., Schumann K., Neuenhahn M., Schober K., Busch D.H. 2021. Targeted T cell receptor gene editing provides predictable T cell product function for immunotherapy. Cell Rep Med 2, 100374. doi:10.1016/j.xcrm.2021.100374.
6. Flommersfeld S., Böttcher J.P., Ersching J., Flossdorf M., Meiser P., Pachmayr L.O., Leube J., Hensel I., Jarosch S., Zhang Q., Chaudhry M.Z., Andrae I., Schiemann M., Busch D.H., Cicin-Sain L., Sun J.C., Gasteiger G., Victora G.D., Hofer T., Buchholz V.R. Grassmann, S. 2021. Fate mapping of single NK cells identifies a type 1 innate lymphoid-like lineage that bridges innate and adaptive recognition of viral infection. Immunity 54, 2288-2304 e2287. doi:10.1016/j.immuni.2021.08.002.
7. Leube J., Mühlbauer A., Andrä I., Biggel M., Busch D.H., Kretschmer L., Buchholz V.R. 2023. Single-cell fate mapping reveals widespread clonal ignorance of low-affinity T cells exposed to systemic infection. Eur J Immunol 53, e2250009. doi:10.1002/eji.202250009.
8. Buck M.C., Bast L., Hecker J.S., Riviere J., Rothenberg-Thurley M., Vogel L., Wang D., Andrä I., Theis F.J., Bassermann F., Metzeler K.H., Oostendorp R.A.J., Marr C., Götze K.S. 2023. Progressive disruption of hematopoietic architecture from clonal hematopoiesis to MDS. iScience 26, 107328. doi:10.1016/j.isci.2023.107328.
Head of Flow Cytometry Core Unit
Institute for Medical Microbiology, Immunology and Hygiene
TUM Munich